Journal ArticleDOI
The endometrial receptivity array for diagnosis and personalized embryo transfer as a treatment for patients with repeated implantation failure.
Maria Ruiz-Alonso,David Blesa,Patricia Diaz-Gimeno,Eva Gómez,Manuel Fernández-Sánchez,F. Carranza,Joan Carrera,F. Vilella,Antonio Pellicer,Carlos Simón +9 more
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TLDR
There is an increased percentage of WOI displacement in RIF patients compared with comparison group patients, leading to the concept of pET as a therapeutic strategy.About:
This article is published in Fertility and Sterility.The article was published on 2013-09-01. It has received 351 citations till now.read more
Citations
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Journal ArticleDOI
What a difference two days make: “personalized” embryo transfer (pET) paradigm: A case report and pilot study
TL;DR: A clinical case of successful personalized embryo transfer (pET) is reported after four IVF and three oocyte donation failed attempts in which different embryo transfer strategies were attempted and illustrates the utility of a personalized endometrial diagnostic approach.
Journal ArticleDOI
Rate of true recurrent implantation failure is low: results of three successive frozen euploid single embryo transfers.
Paul Pirtea,Dominique de Ziegler,Xin Tao,Li Sun,Yiping Zhan,Jean-Marc Ayoubi,Emre Seli,Jason M. Franasiak,Richard T. Scott +8 more
TL;DR: The findings suggest that true recurrent implantation failure is rare, for those patients with the ability to make euploid blastocysts, <5% would fail to achieve a clinical pregnancy with three embryos transferred.
Journal ArticleDOI
A pilot study and case reports on endometrial microbiota and pregnancy outcome: An analysis using 16S rRNA gene sequencing among IVF patients, and trial therapeutic intervention for dysbiotic endometrium.
TL;DR: Report cases who were treated for NLDM concurrently with antibiotics and prebiotic/probiotic supplements in a Japanese infertile population are reported.
Journal ArticleDOI
Endometrial pattern, but not endometrial thickness, affects implantation rates in euploid embryo transfers.
Julian A. Gingold,Joseph A. Lee,Jorge Rodriguez-Purata,Michael Whitehouse,Benjamin Sandler,Lawrence Grunfeld,Tanmoy Mukherjee,Alan B. Copperman +7 more
TL;DR: Within the study population, EnT was not significantly associated with clinical outcomes of euploid ETs, and a type 3 EnP at trigger day suggests a prematurely closed window of implantation.
References
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Journal ArticleDOI
Molecular Phenotyping of Human Endometrium Distinguishes Menstrual Cycle Phases and Underlying Biological Processes in Normo-Ovulatory Women
Said Talbi,A.E. Hamilton,Kim Chi Vo,Suzana Tulac,Michael Toft Overgaard,Chrysoula Dosiou,N Le Shay,C.N. Nezhat,R Kempson,Bruce A. Lessey,Nihar R. Nayak,Linda C. Giudice +11 more
TL;DR: Endometrial samples obtained by two different sampling techniques from subjects who are as normal as possible in a human study and including those with unknown histology, can be classified by their molecular signatures and correspond to known phases of the menstrual cycle with identical results using two independent analytical methods.
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A genomic diagnostic tool for human endometrial receptivity based on the transcriptomic signature
Patricia Diaz-Gimeno,José A. Horcajadas,José Antonio Martínez-Conejero,Francisco J. Esteban,Pilar Alamá,Antonio Pellicer,Carlos Simón +6 more
TL;DR: A genomic tool composed of a customized microarray and a bioinformatic predictor for endometrial dating and to detect pathologies ofendometrial origin can be used clinically in reproductive medicine and gynecology and the transcriptomic signature is a potential endometrian receptivity biomarkers cluster.
Journal ArticleDOI
Local injury to the endometrium doubles the incidence of successful pregnancies in patients undergoing in vitro fertilization.
TL;DR: It is suggested that IVF treatment that is preceded by endometrial biopsy doubles the chance for a take-home baby.
Journal ArticleDOI
Investigation and treatment of repeated implantation failure following IVF-ET
TL;DR: The suggested methods for evaluation and treatment of RIF are discussed: repeated hysteroscopy, myomectomy, endometrial stimulation, immunotherapy, preimplantation genetic screening (PGS), assisted hatching, zygote intra-Fallopian transfer (ZIFT), co-culture, blastocyst transfer, cytoplasmic transfer, tailoring stimulation protocols and salpingectomy for hydrosalpinges.
Journal ArticleDOI
Gene expression profiling of human endometrial receptivity on days LH+2 versus LH+7 by microarray technology
Anne Riesewijk,Julio Martín,Roselinde van Os,José A. Horcajadas,Jan Polman,Antonio Pellicer,Sietse Mosselman,Carlos Simón +7 more
TL;DR: Gene expression profiles of pre-receptive versus receptive endometria obtained from the same fertile woman in the same menstrual cycle are compared to gain a global molecular understanding of human endometrial receptivity.