Journal ArticleDOI
The endometrial receptivity array for diagnosis and personalized embryo transfer as a treatment for patients with repeated implantation failure.
Maria Ruiz-Alonso,David Blesa,Patricia Diaz-Gimeno,Eva Gómez,Manuel Fernández-Sánchez,F. Carranza,Joan Carrera,F. Vilella,Antonio Pellicer,Carlos Simón +9 more
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TLDR
There is an increased percentage of WOI displacement in RIF patients compared with comparison group patients, leading to the concept of pET as a therapeutic strategy.About:
This article is published in Fertility and Sterility.The article was published on 2013-09-01. It has received 351 citations till now.read more
Citations
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Journal ArticleDOI
Commercially Available Molecular Approaches to Evaluate Endometrial Receptivity: A Systematic Review and Critical Analysis of the Literature
Evangelos Maziotis,Theodoros Kalampokas,Polina Giannelou,Sokratis Grigoriadis,Anna Rapani,Marios Anifantakis,Amalia Kotsifaki,A. L. Pantou,Olga Triantafyllidou,Despoina Tzanakaki,Spyridoula Neofytou,Paraskevi Vogiatzi,Panagiotis Bakas,Maria Simopoulou,Nikolaos Vlahos +14 more
TL;DR: In this article , a systematic review and critical analysis of the existing evidence regarding the employment of commercially available novel approaches to evaluate endometrial receptivity was performed on 1 February 2022.
Journal ArticleDOI
Hypoxia-sensitive miRNA regulation via CRISPR/dCas9 loaded in hybrid exosomes: A novel strategy to improve embryo implantation and prevent placental insufficiency during pregnancy
Alireza Yaghoobi,Yasaman Nazerian,Arman Zeinaddini Meymand,Ali Ansari,A Nazerian,Hassan Niknejad +5 more
TL;DR: In this article , the authors proposed a novel treatment strategy to improve endometrial receptivity and implantation success rate by regulating mir-30d expression as an upstream transcriptomic modifier of the embryo implantation, which resulted in modified expression of the involved genes in embryonic adhesion, invasion, and angiogenesis.
Journal ArticleDOI
Recurrent implantation failure: A comprehensive summary from etiology to treatment
Jun-Yan Ma,Wenyan Gao,Da Li +2 more
TL;DR: In this article , the authors defined recurrent implantation failure (RIF) as a clinical phenomenon characterized by a lack of implantation after the transfer of several embryos and disturbed approximately 10% couples undergoing in vitro fertilization and embryo transfer.
Journal ArticleDOI
Does personalized embryo transfer based on era improve the outcomes in patients with thin endometrium and Rif in Self Versus Donor Programme
Priya Selvaraj,Kamala Selvaraj,Mahalakshmi Sivakumar,Hamini Chandrasekar,Valarmathi Srinivasan +4 more
TL;DR: This study was designed to explore the influence of personalized Embryo Transfer with the guidance of endometrial receptivity array on reproductive outcomes in patients with Recurrent Implantation Failure and thin endometrium, and to determine its efficacy in self versus donor gamete programme.
References
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Journal ArticleDOI
Molecular Phenotyping of Human Endometrium Distinguishes Menstrual Cycle Phases and Underlying Biological Processes in Normo-Ovulatory Women
Said Talbi,A.E. Hamilton,Kim Chi Vo,Suzana Tulac,Michael Toft Overgaard,Chrysoula Dosiou,N Le Shay,C.N. Nezhat,R Kempson,Bruce A. Lessey,Nihar R. Nayak,Linda C. Giudice +11 more
TL;DR: Endometrial samples obtained by two different sampling techniques from subjects who are as normal as possible in a human study and including those with unknown histology, can be classified by their molecular signatures and correspond to known phases of the menstrual cycle with identical results using two independent analytical methods.
Journal ArticleDOI
A genomic diagnostic tool for human endometrial receptivity based on the transcriptomic signature
Patricia Diaz-Gimeno,José A. Horcajadas,José Antonio Martínez-Conejero,Francisco J. Esteban,Pilar Alamá,Antonio Pellicer,Carlos Simón +6 more
TL;DR: A genomic tool composed of a customized microarray and a bioinformatic predictor for endometrial dating and to detect pathologies ofendometrial origin can be used clinically in reproductive medicine and gynecology and the transcriptomic signature is a potential endometrian receptivity biomarkers cluster.
Journal ArticleDOI
Local injury to the endometrium doubles the incidence of successful pregnancies in patients undergoing in vitro fertilization.
TL;DR: It is suggested that IVF treatment that is preceded by endometrial biopsy doubles the chance for a take-home baby.
Journal ArticleDOI
Investigation and treatment of repeated implantation failure following IVF-ET
TL;DR: The suggested methods for evaluation and treatment of RIF are discussed: repeated hysteroscopy, myomectomy, endometrial stimulation, immunotherapy, preimplantation genetic screening (PGS), assisted hatching, zygote intra-Fallopian transfer (ZIFT), co-culture, blastocyst transfer, cytoplasmic transfer, tailoring stimulation protocols and salpingectomy for hydrosalpinges.
Journal ArticleDOI
Gene expression profiling of human endometrial receptivity on days LH+2 versus LH+7 by microarray technology
Anne Riesewijk,Julio Martín,Roselinde van Os,José A. Horcajadas,Jan Polman,Antonio Pellicer,Sietse Mosselman,Carlos Simón +7 more
TL;DR: Gene expression profiles of pre-receptive versus receptive endometria obtained from the same fertile woman in the same menstrual cycle are compared to gain a global molecular understanding of human endometrial receptivity.