Journal ArticleDOI
The endometrial receptivity array for diagnosis and personalized embryo transfer as a treatment for patients with repeated implantation failure.
Maria Ruiz-Alonso,David Blesa,Patricia Diaz-Gimeno,Eva Gómez,Manuel Fernández-Sánchez,F. Carranza,Joan Carrera,F. Vilella,Antonio Pellicer,Carlos Simón +9 more
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TLDR
There is an increased percentage of WOI displacement in RIF patients compared with comparison group patients, leading to the concept of pET as a therapeutic strategy.About:
This article is published in Fertility and Sterility.The article was published on 2013-09-01. It has received 351 citations till now.read more
Citations
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Journal ArticleDOI
Immunohistochemical criteria for endometrial receptivity in I/II stage endometriosis IVF-treated patients
Y Krylova,V. O. Polyakova,Igor M. Kvetnoy,Igor Yu. Kogan,Lyailya Kh. Dzhemlikhanova,Dariko A. Niauri,A. M. Gzgzyan,E Ailamazyan +7 more
TL;DR: A discriminant analysis of key biological molecules participating in implant window formation demonstrated that highest information capacity was characteristic for LIF expression percent area, integrin αVβ3 both percent area and optic density in endometrial stroma and glands.
Journal ArticleDOI
Infertility diagnosis has a significant impact on the transcriptome of developing blastocysts.
Blair R. McCallie,Jason C. Parks,Darren K. Griffin,William B. Schoolcraft,Mandy G. Katz-Jaffe +4 more
TL;DR: Underlying patient infertility diagnosis has an impact on the blastocyst transcriptome, modifying gene expression associated with developmental competence and implantation potential.
Journal ArticleDOI
iTRAQ comparison of proteomic profiles of endometrial receptivity
Silvia Pérez-Debén,José Bellver,Pilar Alamá,Stefania Salsano,Alicia Quiñonero,Patricia Sebastian-Leon,Patricia Diaz-Gimeno,Francisco Domínguez +7 more
TL;DR: It is confirmed that an IUD introduces numerous changes in the endometrial protein profile when compared to fertile and RIF endometria, revealing some key proteins involved in endometrian receptivity.
Journal ArticleDOI
Endometrial miRNome profile according to the receptivity status and implantation failure
Loubna Drissennek,Chloé Baron,Sophie Brouillet,Frida Entezami,Frida Entezami,Samir Hamamah,Delphine Haouzi +6 more
TL;DR: The miRNome profile of endometrial tissues during the implantation window can predict the pregnancy outcome and these data are crucial for opening new perspectives to predict implantation failure and consequently, to increase ART success.
Journal ArticleDOI
Uterine fluid microRNAs are dysregulated in women with recurrent implantation failure
Carolina von Grothusen,Caroline Frisendahl,Vijayachitra Modhukur,P.G.L. Lalitkumar,Maire Peters,Omid R. Faridani,Andres Salumets,Nageswara Rao Boggavarapu,Kristina Gemzell-Danielsson +8 more
TL;DR: Several of the differentially abundant miRNAs found in uterine fluid of women with recurrent implantation failure are reported in endometrial epithelial cells and in association with endometrian receptivity and RIF, and need to be confirmed and further explored in vitro.
References
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Journal ArticleDOI
Molecular Phenotyping of Human Endometrium Distinguishes Menstrual Cycle Phases and Underlying Biological Processes in Normo-Ovulatory Women
Said Talbi,A.E. Hamilton,Kim Chi Vo,Suzana Tulac,Michael Toft Overgaard,Chrysoula Dosiou,N Le Shay,C.N. Nezhat,R Kempson,Bruce A. Lessey,Nihar R. Nayak,Linda C. Giudice +11 more
TL;DR: Endometrial samples obtained by two different sampling techniques from subjects who are as normal as possible in a human study and including those with unknown histology, can be classified by their molecular signatures and correspond to known phases of the menstrual cycle with identical results using two independent analytical methods.
Journal ArticleDOI
A genomic diagnostic tool for human endometrial receptivity based on the transcriptomic signature
Patricia Diaz-Gimeno,José A. Horcajadas,José Antonio Martínez-Conejero,Francisco J. Esteban,Pilar Alamá,Antonio Pellicer,Carlos Simón +6 more
TL;DR: A genomic tool composed of a customized microarray and a bioinformatic predictor for endometrial dating and to detect pathologies ofendometrial origin can be used clinically in reproductive medicine and gynecology and the transcriptomic signature is a potential endometrian receptivity biomarkers cluster.
Journal ArticleDOI
Local injury to the endometrium doubles the incidence of successful pregnancies in patients undergoing in vitro fertilization.
TL;DR: It is suggested that IVF treatment that is preceded by endometrial biopsy doubles the chance for a take-home baby.
Journal ArticleDOI
Investigation and treatment of repeated implantation failure following IVF-ET
TL;DR: The suggested methods for evaluation and treatment of RIF are discussed: repeated hysteroscopy, myomectomy, endometrial stimulation, immunotherapy, preimplantation genetic screening (PGS), assisted hatching, zygote intra-Fallopian transfer (ZIFT), co-culture, blastocyst transfer, cytoplasmic transfer, tailoring stimulation protocols and salpingectomy for hydrosalpinges.
Journal ArticleDOI
Gene expression profiling of human endometrial receptivity on days LH+2 versus LH+7 by microarray technology
Anne Riesewijk,Julio Martín,Roselinde van Os,José A. Horcajadas,Jan Polman,Antonio Pellicer,Sietse Mosselman,Carlos Simón +7 more
TL;DR: Gene expression profiles of pre-receptive versus receptive endometria obtained from the same fertile woman in the same menstrual cycle are compared to gain a global molecular understanding of human endometrial receptivity.