Journal ArticleDOI
The endometrial receptivity array for diagnosis and personalized embryo transfer as a treatment for patients with repeated implantation failure.
Maria Ruiz-Alonso,David Blesa,Patricia Diaz-Gimeno,Eva Gómez,Manuel Fernández-Sánchez,F. Carranza,Joan Carrera,F. Vilella,Antonio Pellicer,Carlos Simón +9 more
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TLDR
There is an increased percentage of WOI displacement in RIF patients compared with comparison group patients, leading to the concept of pET as a therapeutic strategy.About:
This article is published in Fertility and Sterility.The article was published on 2013-09-01. It has received 351 citations till now.read more
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Journal ArticleDOI
Cyclic decidualization of the human endometrium in reproductive health and failure.
Birgit Gellersen,Jan J. Brosens +1 more
TL;DR: The endocrine, paracrine, and autocrine cues that tightly govern this differentiation process are reviewed and how disorders that subvert the programming, initiation, or progression of decidualization compromise reproductive health and predispose for pregnancy failure is discussed.
Journal ArticleDOI
Evidence that the endometrial microbiota has an effect on implantation success or failure
Inmaculada Moreno,Francisco M. Codoñer,Felipe Vilella,Diana Valbuena,Juan F. Martinez-Blanch,Jorge Jimenez-Almazán,Roberto Alonso,Pilar Alamá,José Remohí,Antonio Pellicer,Daniel Ramón,Carlos Simón +11 more
TL;DR: The results demonstrate the existence of an endometrial microbiota that is highly stable during the acquisition of endometrian receptivity, however, pathological modification of its profile is associated with poor reproductive outcomes for in vitro fertilization patients.
Journal ArticleDOI
Recurrent Implantation Failure-update overview on etiology, diagnosis, treatment and future directions
TL;DR: A new initial step in approach to patients with RIF is suggested, individualized planned activities to activate the brain's reward system in attempt to improve immunological balance in the body.
Journal ArticleDOI
Fresh versus frozen embryo transfer: backing clinical decisions with scientific and clinical evidence
Jemma Evans,Natalie J. Hannan,Tracey A. Edgell,Beverley Vollenhoven,Peter Lutjen,Tiki Osianlis,Lois A. Salamonsen,Lois A. Salamonsen,Luk Rombauts +8 more
TL;DR: The literature demonstrates reduced endometrial receptivity in controlled ovarian stimulation cycles and supports the clinical observations that FET reduces the risk of ovarian hyperstimulation syndrome and improves outcomes for both the mother and baby.
Journal ArticleDOI
Conventional and modern markers of endometrial receptivity: a systematic review and meta-analysis.
Laurentiu Craciunas,Ioannis D. Gallos,Justin Chu,Tom Bourne,Siobhan Quenby,Jan J. Brosens,Arri Coomarasamy +6 more
TL;DR: The post-test probabilities from the analyses may be used in clinical practice to manage couples' expectations during fertility treatments (IUI and IVF), and it is proposed that various levels of endometrial receptivity exist within the window of implantation.
References
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Journal ArticleDOI
Treatment of repeated unexplained in vitro fertilization failure with intravenous immunoglobulin: a randomized, placebo-controlled Canadian trial.
TL;DR: In this article, the authors evaluated the effect of intravenous immunoglobulin (IVIG) on pregnancy outcome in couples with repeated unexplained in vitro fertilization (IVF) failure.
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Recurrent IVF failure: other factors
TL;DR: The impact of obesity, cigarette smoke, uterine anatomy, body mass index, thyroid dysfunction, immune factors, the hereditary and acquired thrombophilias, and embryo transfer technique on recurrent IVF failure is examined.
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Gene expression in cultured endometrium from women with different outcomes following IVF.
TL;DR: Although microarray profiling may currently not be sensitive enough for studying the effects of embryo-derived factors on the endometrium, the observed differences in gene expression between M and OP suggest that it will become an interesting tool for the identification of fertility-relevant markers produced by theendometrium.
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Defective endometrial prostaglandin synthesis identified in patients with repeated implantation failure undergoing in vitro fertilization
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A study of endometrial morphology in women who failed to conceive in a donor insemination programme.
TL;DR: Examination of the morphology of endometrium in women who failed to conceive after nine or more cycles of donor insemination treatment finds no change in morphology.