Journal ArticleDOI
The role of iodine in human growth and development.
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TLDR
Iodine prophylaxis of deficient populations with periodic monitoring is an extremely cost effective approach to reduce the substantial adverse effects of iodine deficiency throughout the life cycle.About:
This article is published in Seminars in Cell & Developmental Biology.The article was published on 2011-08-01. It has received 295 citations till now. The article focuses on the topics: Iodine deficiency & Cretinism.read more
Citations
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Fish intake during pregnancy and foetal neurodevelopment--a systematic review of the evidence.
TL;DR: The benefits of diets providing moderate amounts of fish during pregnancy outweigh potential detrimental effects in regards to offspring neurodevelopment, and it is important that the type of fish consumed is low in mercury.
Journal ArticleDOI
Eukaryotic resistance to fluoride toxicity mediated by a widespread family of fluoride export proteins
Sanshu Li,Kathryn D. Smith,Jared H. Davis,Patricia B. Gordon,Ronald R. Breaker,Scott A. Strobel +5 more
TL;DR: It is demonstrated that a protein called FEX in many fungi is essential for cell survival in the presence of high fluoride concentrations, indicating that many eukaryotic species that carry FEX genes likely avoid fluoride toxicity by purging cellular fluoride.
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Low Urinary Iodine Excretion during Early Pregnancy Is Associated with Alterations in Executive Functioning in Children
Nina H. van Mil,Henning Tiemeier,Jacoba J. Bongers-Schokking,Akhgar Ghassabian,Albert Hofman,Herbert Hooijkaas,Vincent W. V. Jaddoe,Sabine M.P.F. de Muinck Keizer-Schrama,Eric A.P. Steegers,Theo J. Visser,Willy Visser,H. Alec Ross,Frank C. Verhulst,Yolanda B. de Rijke,Régine P.M. Steegers-Theunissen +14 more
TL;DR: Low maternal urinary iodine during pregnancy is associated with impaired executive functioning in children at 4 y of age, and future studies are needed to show whether these children are more vulnerable to develop later clinical disorders.
Journal ArticleDOI
Early weaning PCB 95 exposure alters the neonatal endocrine system: thyroid adipokine dysfunction
TL;DR: The results imply that PCB 95 may act as a disruptor of the developmental hypothalamic-pituitary-thyroid axis and Hypothyroidism caused by PCB95 may impair the adipokine axis, fat metabolism, and in general postnatal development.
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Recent Insights into the Cell Biology of Thyroid Angiofollicular Units
TL;DR: In thyrocytes, cell polarity is of crucial importance for proper thyroid function, and over time and depending on physiological needs, AFUs may undergo repetitive phases of high, moderate, or low cell and tissue activity, which may ultimately culminate in multinodular goiters.
References
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Journal ArticleDOI
Dietary reference intakes: vitamin A, vitamin K, arsenic, boron, chromium, copper, iodine, iron, manganese, molybdenum, nickel, silicon, vanadium, and zinc.
TL;DR: The DRIs represent the new approach adopted by the Food and Nutrition Board to providing quantitative estimates of nutrient intakes for use in a variety of settings, replacing and expanding on the past 50 years of periodic updates and revisions of the Recommended Dietary Allowances.
Journal ArticleDOI
Insulin-Like Growth Factors and Their Binding Proteins: Biological Actions*
J. I. Jones,David R. Clemmons +1 more
TL;DR: In recognition of its generalized pleiotypic actions, sulfation factor was renamed somatomedin (mediator of the effects of somatotropin) and was included in the emerging classification of broad spectrum growth factors along with platelet derived growth factor, fibroblast growth factors, and epidermal growth factor.
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Maternal thyroid deficiency during pregnancy and subsequent neuropsychological development of the child.
James E. Haddow,Glenn E. Palomaki,Walter C. Allan,Josephine Williams,George J. Knight,June Gagnon,Cheryl E. O’heir,Marvin L. Mitchell,Rosalie J. Hermos,Susan E. Waisbren,James D. Faix,Robert Z. Klein +11 more
TL;DR: Undiagnosed hypothyroidism in pregnant women may adversely affect their fetuses; therefore, screening for thyroid deficiency during pregnancy may be warranted.
Book
Dietary reference intakes for vitamin A, vitamin K, arsenic, boron, chromium, copper, iodine, iron, manganese, molybdenum, nickel, silicon, vanadium, and zinc : a report of the Panel on Micronutrients, Subcommittees on Upper Reference Levels of Nutrients and of Interpretation and Use of Dietary Reference Intakes, and the Standing Committee on the Scientific Evaluation of Dietary Reference Intakes, Food and Nutrition Board, Institute of Medicine
TL;DR: In this article, a review of the scientific literature regarding dietary micronutrients, recommendations have been formulated regarding vitamins A and K, iron, iodine, chromium, copper, manganese, molybdenum, zinc, and other potentially beneficial trace elements such as boron to determine the roles, if any, they play in health.
Journal ArticleDOI
Impaired spatial learning in alpha-calcium-calmodulin kinase II mutant mice
TL;DR: The data considerably strengthen the contention that the synaptic changes exhibited in LTP are the basis for spatial memory.