The synthesis of complex-type oligosaccharides. I. Structure of the lipid-linked oligosaccharide precursor of the complex-type oligosaccharides of the vesicular stomatitis virus G protein.
E. Li,Ira Tabas,Stuart Kornfeld +2 more
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The synthesis of the complex-type oligosaccharide unit of the vesicular stomatitis virus G protein is initiated by the en bloc transfer of a high molecular weight oligosACcharide from a lipid carrier to the nascent polypeptide.About:
This article is published in Journal of Biological Chemistry.The article was published on 1978-11-10 and is currently open access. It has received 398 citations till now. The article focuses on the topics: Oligosaccharide & Mannose.read more
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Glucose starvation alters lipid-linked oligosaccharide biosynthesis in Chinese hamster ovary cells.
TL;DR: These findings demonstrate that Chinese hamster ovary cells utilize an alternate glycosylation pathway when deprived of glucose.
Journal ArticleDOI
Purification of cell membrane glycoproteins by lectin affinity chromatography.
Reuben Lotan,Garth L. Nicolson +1 more
TL;DR: Approaches useful for the purification and characterization of cell membrane lectin- binding components and applications of immobilized lectins for fractionation and purification of membrane glycoproteins.
Journal ArticleDOI
Distribution of terminal glycosyltransferases in hepatic Golgi fractions.
R Bretz,H Bretz,G E Palade +2 more
TL;DR: The distribution of the three glycosyltransferases synthesizing the terminal trisaccharide sialic acid yields D-galactose yields N- acetylglucosamine present in many glycoproteins was determined in Golgi fractions prepared from rat liver homogenates by a modification of the procedure of Ehrenreich et al.
Book ChapterDOI
The Lipid Pathway of Protein Glycosylation and its Inhibitors: The Biological Significance of Protein-Bound Carbohydrates
Ralph T. Schwarz,Roelf Datema +1 more
TL;DR: Although 2-deoxy- d -arabinose-hexose has been shown mainly to affect glycosylation (in the systems studied so far), its mode of action in more complex, biological systems may not always depend on its well known property.
Journal ArticleDOI
Substrate specificities of rat liver microsomal glucosidases which process glycoproteins.
L S Grinna,P W Robbins +1 more
TL;DR: It is concluded that rat liver microsomal glucosidases I and II interact with extensive portions of oligosaccharide structure in addition to the glucose residues which they hydrolyze.
References
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TL;DR: Modifications are introduced, based on a test given by Feigl for reducing sugars, which eliminate the heating step, and in which the reagents are applied in organic solvents, thus removing the danger of migration of the sugar spots.
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Determination of aminosugar linkages in glycolipids by methylation: Aminosugar linkages of ceramide pentasaccharides of rabbit erythrocytes and of Forssman antigen☆
TL;DR: This method was successfully applied to analysis of aminosugar linkages in blood group B-active ceramide pentasaccharide from rabbit erythrocytes and in Forssman antigen of equine spleen.
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The role of polyprenol-linked sugars in glycoprotein synthesis.
C J Waechter,W J Lennarz +1 more
TL;DR: The chiral stationary phase for lipid-Linked Monosaccharides showed good chiral recognition ability towards various lipids, and this property has been generalized to other lipids as well.
Book ChapterDOI
[90] α-Mannosidase, β-N-acetylhexosaminidase, and β-galactosidase from jack bean meal
Yu-Teh Li,Su-Chen Li +1 more
Journal ArticleDOI
Structural studies of two ovalbumin glycopeptides in relation to the endo-beta-N-acetylglucosaminidase specificity.
T Tai,Katsuko Yamashita,M Ogata-Arakawa,Norio Koide,Takashi Muramatsu,Shintaro Iwashita,Y Inoue,Akira Kobata +7 more
TL;DR: The presence of the unsubstituted alpha-mannosyl residue linked at the C-3 position of the terminal mannose of Manbeta1 leads to 4 GlcNAcAsn core must be essential for the action of the enzyme.