The synthesis of complex-type oligosaccharides. I. Structure of the lipid-linked oligosaccharide precursor of the complex-type oligosaccharides of the vesicular stomatitis virus G protein.
E. Li,Ira Tabas,Stuart Kornfeld +2 more
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The synthesis of the complex-type oligosaccharide unit of the vesicular stomatitis virus G protein is initiated by the en bloc transfer of a high molecular weight oligosACcharide from a lipid carrier to the nascent polypeptide.About:
This article is published in Journal of Biological Chemistry.The article was published on 1978-11-10 and is currently open access. It has received 398 citations till now. The article focuses on the topics: Oligosaccharide & Mannose.read more
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Asparagine-linked glycoprotein biosynthesis in rat brain: Identification of glucosidase I, glucosidase II, and an endomannosidase (glucosyl mannosidase)☆
TL;DR: It is indicated that the brain, like other tissues, contains glucosidases I and II, and an endo enzyme (glucosyl mannosidase) in rat brain is characterized, which appears to be an intrinsic microsomal membrane component.
Journal ArticleDOI
Crystal Structure and Functional Analyses of the Lectin Domain of Glucosidase II: Insights into Oligomannose Recognition
Linda J. Olson,Ramiro Orsi,Francis C. Peterson,Armando J. Parodi,Jung-Ja P. Kim,Cecilia D'Alessio,Cecilia D'Alessio,Nancy M. Dahms +7 more
TL;DR: Comparing ligand-bound and unbound structures reveals no major difference in their overall fold, but rather a repositioning of side chains throughout the binding pocket, including Y372, demonstrating an important role for Y372 in regulating GII activity.
Journal ArticleDOI
Synthesis of an octasaccharide fragment of high-mannose-type glycans of glycoproteins.
TL;DR: Crucial glycosylation of trisaccharide intermediate, benzyl O-(2,4-di-O-benzyl-beta-D-mannopyranosyl)-(1----4)-O-(2-acetamido-3,6-di -O- benzyl-2-deoxy-beta
Journal ArticleDOI
Effects of brefeldin A on the synthesis and secretion of egg white proteins in primary cultured oviduct cells of laying Japanese quail (Coturnix coturnix japonica).
TL;DR: The results suggest that the conversion of high-mannose-type oligosaccharides to hybrid-type ones, which is not usually observed in mammalian species but only in avian oviduct tissues, proceeds between the Golgi complex and the endoplasmic reticulum.
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Biosynthesis of the major human red cell sialoglycoprotein, glycophorin A: A review
Carl G. Gahmberg,Mikko Jokinen,Kimmo K. Karhi,Ismo Ulmanen,Leevi Kääriäinen,Leif C. Andersson +5 more
TL;DR: The human leukemia cell line K562 is erythroid and expresses the major red cell sialoglycoprotein, glycophorin A, and the biosynthesis of glycophOrin A after pulse-chase labeling with [35S] methionine is studied.
References
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TL;DR: This method was successfully applied to analysis of aminosugar linkages in blood group B-active ceramide pentasaccharide from rabbit erythrocytes and in Forssman antigen of equine spleen.
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The role of polyprenol-linked sugars in glycoprotein synthesis.
C J Waechter,W J Lennarz +1 more
TL;DR: The chiral stationary phase for lipid-Linked Monosaccharides showed good chiral recognition ability towards various lipids, and this property has been generalized to other lipids as well.
Book ChapterDOI
[90] α-Mannosidase, β-N-acetylhexosaminidase, and β-galactosidase from jack bean meal
Yu-Teh Li,Su-Chen Li +1 more
Journal ArticleDOI
Structural studies of two ovalbumin glycopeptides in relation to the endo-beta-N-acetylglucosaminidase specificity.
T Tai,Katsuko Yamashita,M Ogata-Arakawa,Norio Koide,Takashi Muramatsu,Shintaro Iwashita,Y Inoue,Akira Kobata +7 more
TL;DR: The presence of the unsubstituted alpha-mannosyl residue linked at the C-3 position of the terminal mannose of Manbeta1 leads to 4 GlcNAcAsn core must be essential for the action of the enzyme.