scispace - formally typeset
Open AccessJournal ArticleDOI

The synthesis of complex-type oligosaccharides. I. Structure of the lipid-linked oligosaccharide precursor of the complex-type oligosaccharides of the vesicular stomatitis virus G protein.

E. Li, +2 more
- 10 Nov 1978 - 
- Vol. 253, Iss: 21, pp 7762-7770
Reads0
Chats0
TLDR
The synthesis of the complex-type oligosaccharide unit of the vesicular stomatitis virus G protein is initiated by the en bloc transfer of a high molecular weight oligosACcharide from a lipid carrier to the nascent polypeptide.
About
This article is published in Journal of Biological Chemistry.The article was published on 1978-11-10 and is currently open access. It has received 398 citations till now. The article focuses on the topics: Oligosaccharide & Mannose.

read more

Citations
More filters
Journal ArticleDOI

A new yeast mutation in the glucosylation steps of the asparagine-linked glycosylation pathway: formation of a novel asparagine-linked oligosaccharide containing two glucose residues

TL;DR: A novel Glc2 compound was probably produced by the action of the biosynthetic enzyme that normally adds the alpha 1,2-linked glucose to lipid-linked Glc 2Man9GlcNAc2, and this enzyme may be able to slowly addalpha 1, 2- linked glucose residue to protein-bound Glc1Man9 gls1-1 haploid double mutant.
Journal ArticleDOI

Structural studies of the major high mannose oligosaccharide units from Chinese hamster ovary cell glycoproteins.

TL;DR: It is proposed that the high mannose-type oligosaccharides present in Chinese hamster ovary cells are a product of "incomplete" processing of the protein-bound oligOSaccharide along the same pathway which leads ultimately to the formation of a complex- type oligosACcharide.
Journal ArticleDOI

Selective retention of monoglucosylated high mannose oligosaccharides by a class of mutant vesicular stomatitis virus G proteins.

TL;DR: Results suggest that aberrant G proteins are selectively modified by resident ER enzymes to retain monoglucosylated oligosaccharides.
Journal ArticleDOI

Biosynthesis of yeast mannoproteins. Synthesis of mannan outer chain and of dolichol derivatives.

TL;DR: It is concluded that dolichol monophosphate mannose is not an intermediate in the synthesis of the outer chain and that this part of mannan and the dlichol diphosphate oligosaccharides are synthesized by different mannosyltransferases.
References
More filters
Journal ArticleDOI

Detection of sugars on paper chromatograms.

W E Trevelyan, +2 more
- 09 Sep 1950 - 
TL;DR: Modifications are introduced, based on a test given by Feigl for reducing sugars, which eliminate the heating step, and in which the reagents are applied in organic solvents, thus removing the danger of migration of the sugar spots.
Journal ArticleDOI

Determination of aminosugar linkages in glycolipids by methylation: Aminosugar linkages of ceramide pentasaccharides of rabbit erythrocytes and of Forssman antigen☆

TL;DR: This method was successfully applied to analysis of aminosugar linkages in blood group B-active ceramide pentasaccharide from rabbit erythrocytes and in Forssman antigen of equine spleen.
Journal ArticleDOI

The role of polyprenol-linked sugars in glycoprotein synthesis.

TL;DR: The chiral stationary phase for lipid-Linked Monosaccharides showed good chiral recognition ability towards various lipids, and this property has been generalized to other lipids as well.
Journal ArticleDOI

Structural studies of two ovalbumin glycopeptides in relation to the endo-beta-N-acetylglucosaminidase specificity.

TL;DR: The presence of the unsubstituted alpha-mannosyl residue linked at the C-3 position of the terminal mannose of Manbeta1 leads to 4 GlcNAcAsn core must be essential for the action of the enzyme.
Related Papers (5)