The synthesis of complex-type oligosaccharides. I. Structure of the lipid-linked oligosaccharide precursor of the complex-type oligosaccharides of the vesicular stomatitis virus G protein.
E. Li,Ira Tabas,Stuart Kornfeld +2 more
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The synthesis of the complex-type oligosaccharide unit of the vesicular stomatitis virus G protein is initiated by the en bloc transfer of a high molecular weight oligosACcharide from a lipid carrier to the nascent polypeptide.About:
This article is published in Journal of Biological Chemistry.The article was published on 1978-11-10 and is currently open access. It has received 398 citations till now. The article focuses on the topics: Oligosaccharide & Mannose.read more
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Quality control of glycoprotein folding and ERAD: the role of N-glycan handling, EDEM1 and OS-9.
Jürgen Roth,Christian Zuber +1 more
TL;DR: This review summarizes current knowledge concerning the role played by glucosidases I and II, in concert with the bifunctional glucosyltransferase and calnexin/calreticulin in glycoprotein folding, the role of conventional ER mannosidase I inconcert with the mannosidsase EDEM1 in handling and routing of misfolded glycoproteins, and how the b ifunctional OS-9 provides a link to the ER dislocon
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Structures of the oligosaccharides present at the three asparagine-linked glycosylation sites of human IgD.
S J Mellis,J U Baenziger +1 more
TL;DR: IgD:WAH is notable for the presence of virtually unprocessed oligosaccharide structures (glucosylated high mannose) on the same peptide backbone as extensively processed complex type molecules.
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Abnormal glycosylation of human fibronectin secreted in the presence of monensin.
TL;DR: It is suggested that monensin, by impairing intracellular translocation through the Golgi region, allows incompletely processed forms of fibronectin to reach the cell surface and to be released into the culture medium.
Journal ArticleDOI
Identification of the mannosyl donors involved in the synthesis of lipid-linked oligosaccharides.
Journal ArticleDOI
Lipid-bound saccharides in Rhizobium meliloti.
TL;DR: The lipid-bound saccharides formed by incubation of uridine diphosphate glucose with a particulate enzyme of Rhizobium meliloti were studied and it was shown that the sequence is: first, galactose and glucosyl beta 1-3 Galactose, then the rest of glucose residues, and finally, the substituents (acetyl and pyruvic acid).
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TL;DR: The chiral stationary phase for lipid-Linked Monosaccharides showed good chiral recognition ability towards various lipids, and this property has been generalized to other lipids as well.
Book ChapterDOI
[90] α-Mannosidase, β-N-acetylhexosaminidase, and β-galactosidase from jack bean meal
Yu-Teh Li,Su-Chen Li +1 more
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Structural studies of two ovalbumin glycopeptides in relation to the endo-beta-N-acetylglucosaminidase specificity.
T Tai,Katsuko Yamashita,M Ogata-Arakawa,Norio Koide,Takashi Muramatsu,Shintaro Iwashita,Y Inoue,Akira Kobata +7 more
TL;DR: The presence of the unsubstituted alpha-mannosyl residue linked at the C-3 position of the terminal mannose of Manbeta1 leads to 4 GlcNAcAsn core must be essential for the action of the enzyme.