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Open AccessJournal ArticleDOI

The Taverna workflow suite: designing and executing workflows of Web Services on the desktop, web or in the cloud

TLDR
An update to the taverna tool suite is provided, highlighting new features and developments in the workbench and the Taverna Server.
Abstract
The Taverna workflow tool suite (http://www.taverna.org.uk) is designed to combine distributed Web Services and/or local tools into complex analysis pipelines. These pipelines can be executed on local desktop machines or through larger infrastructure (such as supercomputers, Grids or cloud environments), using the Taverna Server. In bioinformatics, Taverna workflows are typically used in the areas of high-throughput omics analyses (for example, proteomics or transcriptomics), or for evidence gathering methods involving text mining or data mining. Through Taverna, scientists have access to several thousand different tools and resources that are freely available from a large range of life science institutions. Once constructed, the workflows are reusable, executable bioinformatics protocols that can be shared, reused and repurposed. A repository of public workflows is available at http://www.myexperiment.org. This article provides an update to the Taverna tool suite, highlighting new features and developments in the workbench and the Taverna Server.

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Journal ArticleDOI

Cytoscape Automation: empowering workflow-based network analysis.

TL;DR: Cytoscape Automation (CA), which marries CyToscape to highly productive workflow systems, for example, Python/R in Jupyter/RStudio, is described, which exposes over 270 Cytoscapes core functions and 34 apps as REST-callable functions with standardized JSON interfaces backed by Swagger documentation.
Journal ArticleDOI

Pegasus, a workflow management system for science automation

TL;DR: An integrated view of the Pegasus system is provided, showing its capabilities that have been developed over time in response to application needs and to the evolution of the scientific computing platforms.
References
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Journal ArticleDOI

Gapped BLAST and PSI-BLAST: a new generation of protein database search programs.

TL;DR: A new criterion for triggering the extension of word hits, combined with a new heuristic for generating gapped alignments, yields a gapped BLAST program that runs at approximately three times the speed of the original.
Journal ArticleDOI

Galaxy: a comprehensive approach for supporting accessible, reproducible, and transparent computational research in the life sciences

TL;DR: Galaxy Pages are interactive, web-based documents that provide users with a medium to communicate a complete computational analysis and provide support for capturing the context and intent of computational methods.
Journal ArticleDOI

Multiple Sequence Alignment Using ClustalW and ClustalX

TL;DR: The protocols in this unit discuss how to use ClustalX and ClUSTalW to construct an alignment, and create profile alignments by merging existing alignments.
Journal ArticleDOI

Activities at the Universal Protein Resource (UniProt)

Rolf Apweiler, +133 more
TL;DR: The mission of the Universal Protein Resource (UniProt) is to provide the scientific community with a comprehensive, high-quality and freely accessible resource of protein sequences and functional annotation.
Journal ArticleDOI

A new bioinformatics analysis tools framework at EMBL–EBI

TL;DR: A new framework aimed at both novice as well as expert users that exposes novel methods of obtaining annotations and visualizing sequence analysis results through one uniform and consistent interface is presented.
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