Journal ArticleDOI
Thyrotrophin in the pars tuberalis triggers photoperiodic response
Nobuhiro Nakao,Hiroko Ono,Takashi Yamamura,Tsubasa Anraku,Tsuyoshi Takagi,Kumiko Higashi,Shinobu Yasuo,Yasuhiro Katou,Saburo Kageyama,Yumiko Uno,Takeya Kasukawa,Masayuki Iigo,Peter J. Sharp,Atsushi Iwasawa,Yutaka Suzuki,Sumio Sugano,Teruyuki Niimi,Makoto Mizutani,Takao Namikawa,Shizufumi Ebihara,Hiroki R. Ueda,Takashi Yoshimura +21 more
Reads0
Chats0
TLDR
Two waves of gene expression are identified in the quail MBH associated with the initiation of photoinduced secretion of luteinizing hormone and increased TSH in the pars tuberalis seems to trigger long-day photoinduced seasonal breeding.Abstract:
Molecular mechanisms regulating animal seasonal breeding in response to changing photoperiod are not well understood. Rapid induction of gene expression of thyroid-hormone-activating enzyme (type 2 deiodinase, DIO2) in the mediobasal hypothalamus (MBH) of the Japanese quail (Coturnix japonica) is the earliest event yet recorded in the photoperiodic signal transduction pathway. Here we show cascades of gene expression in the quail MBH associated with the initiation of photoinduced secretion of luteinizing hormone. We identified two waves of gene expression. The first was initiated about 14 h after dawn of the first long day and included increased thyrotrophin (TSH) beta-subunit expression in the pars tuberalis; the second occurred approximately 4 h later and included increased expression of DIO2. Intracerebroventricular (ICV) administration of TSH to short-day quail stimulated gonadal growth and expression of DIO2 which was shown to be mediated through a TSH receptor-cyclic AMP (cAMP) signalling pathway. Increased TSH in the pars tuberalis therefore seems to trigger long-day photoinduced seasonal breeding.read more
Citations
More filters
Journal ArticleDOI
Photoperiodic induction without light-mediated circadian entrainment in a High Arctic resident bird
Daniel Appenroth,Vebjørn J. Melum,Alexander C. West,Hugues Dardente,David G. Hazlerigg,Gabriela Wagner +5 more
TL;DR: Data show that the Svalbard ptarmigan does not require circadian entrainment to develop a photoperiodic response involving conserved molecular elements found in temperate species, and is likely to maintain seasonal synchrony in polar regions.
Journal ArticleDOI
Multisensory Non-photoperiodic Cue Advances the Onset of Seasonal Breeding in Island Canaries (Serinus canaria)
TL;DR: It is found that direct exposure of the birds to fresh green vegetation represented the strongest stimulus and advanced breeding by up to 2 months compared to controls, and single non-photoperiodic sensory cues are insufficient to affect the timing of seasonal breeding.
Book ChapterDOI
Arcuate nucleus, median eminence, and hypophysial pars tuberalis.
Horst-Werner Korf,Morten Møller +1 more
TL;DR: The arcuate nucleus (ARC) is located in the mediobasal hypothalamus and forms a morphological and functional entity with the median eminence (ME), the ARC-ME as discussed by the authors.
Journal ArticleDOI
Alternation between short- and long photoperiod reveals hypothalamic gene regulation linked to seasonal body weight changes in Djungarian hamsters (Phodopus sungorus)
TL;DR: The data suggest that body weight regulation appears to be tightly linked to a co‐ordinated regulation of several genes in the hypothalamus, including those involved in thyroid hormone metabolism.
Journal ArticleDOI
Opportunism, photoperiodism, and puberty: Different mechanisms or variations on a theme?
Nicole Perfito,George E. Bentley +1 more
TL;DR: Understanding the mechanisms regulating avian puberty and seasonal breeding might in some cases provide greater insight into the mechanistic control of puberty in nonrodent mammals.
References
More filters
Journal ArticleDOI
Coordinated transcription of key pathways in the mouse by the circadian clock.
Satchidananda Panda,Marina P. Antoch,Brooke H. Miller,Andrew I. Su,Andrew I. Su,Andrew B. Schook,Marty Straume,Peter G. Schultz,Peter G. Schultz,Steve A. Kay,Steve A. Kay,Joseph S. Takahashi,John B. Hogenesch +12 more
TL;DR: Genetic and genomic analysis suggests that a relatively small number of output genes are directly regulated by core oscillator components, and major processes regulated by the SCN and liver were found to be under circadian regulation.
Journal ArticleDOI
Photoperiodic Control of Seasonality in Birds
TL;DR: This review examines how birds use the annual cycle in photoperiod to ensure that seasonal events—breeding, molt, and song production—happen at the appropriate time of year.
Journal ArticleDOI
A transcription factor response element for gene expression during circadian night
Hiroki R. Ueda,Wenbin Chen,Akihito Adachi,Hisanori Wakamatsu,Satoko Hayashi,Tomohiro Takasugi,Mamoru Nagano,Ken-ichi Nakahama,Yutaka Suzuki,Sumio Sugano,Masamitsu Iino,Yasufumi Shigeyoshi,Seiichi Hashimoto +12 more
TL;DR: The role of the Rev-ErbA/ROR response element in gene expression during circadian night is demonstrated, which is in phase with Bmal1 and in antiphase to Per2 oscillations.
Journal ArticleDOI
Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides.
K Maruyama,Sumio Sugano +1 more
TL;DR: Unlike the conventional methods that label the 5' end of cDNAs, this method specifically labels the capped end of the mRNAs with a synthetic r-oligo prior to first-strand cDNA synthesis.
Journal ArticleDOI
Bimodal regulation of mPeriod promoters by CREB-dependent signaling and CLOCK/BMAL1 activity
TL;DR: The results reveal that signaling-dependent activation of mPer genes is distinct from the CLOCK/BMAL1-driven transcription required within the clock feedback loop, and constitute strong evidence that CREB acts as a pivotal endpoint of signaling pathways for the regulation of m per genes.