Traffic-related air pollution, particulate matter, and autism.
TLDR
Exposure to traffic-related air pollution, nitrogen dioxide, PM2.5, and PM10 during pregnancy and during the first year of life was associated with autism.Citations
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Developmental exposure to concentrated ambient ultrafine particulate matter air pollution in mice results in persistent and sex-dependent behavioral neurotoxicity and glial activation.
Joshua L. Allen,Xiufang Liu,Douglas Weston,Lisa Prince,Günter Oberdörster,Jacob N. Finkelstein,Carl J. Johnston,Deborah A. Cory-Slechta +7 more
TL;DR: Findings suggest that neurodevelopment and/or adulthood air pollution exposure may represent a significant underexplored risk factor for central nervous system diseases/disorders and thus a significant public health threat even beyond current appreciation.
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The health impacts of traffic-related exposures in urban areas: Understanding real effects, underlying driving forces and co-producing future directions
Haneen Khreis,Karyn M. Warsow,Ersilia Verlinghieri,Alvaro Guzman,Luc Pellecuer,Luc Pellecuer,António Ferreira,Ian Jones,Eva Heinen,David Rojas-Rueda,Natalie Mueller,Paul Schepers,Karen Lucas,Mark J. Nieuwenhuijsen +13 more
TL;DR: The key driving forces behind the current state of urban mobility are explored, recommendations for practices that could facilitate positioning health at the core of transport design, planning and policy are outlined and stakeholders’ recommendations for a cross-disciplinary co-production approach are outlined.
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Airborne Particulate Matter: Human Exposure and Health Effects.
TL;DR: While the integrated, per capita, exposure of PM for a large fraction of the first-world may be less than 1 mg per day, links between several syndromes, including attention deficit hyperactivity disorder (ADHD), autism, loss of cognitive function, anxiety, asthma, chronic obstructive pulmonary disease (COPD), hypertension, stroke, and PM exposure have been suggested.
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Toxicity of inhaled particulate matter on the central nervous system: neuroinflammation, neuropsychological effects and neurodegenerative disease
Yan Wang,Lilin Xiong,Meng Tang +2 more
TL;DR: Research advances on the health effects of PM with an emphasis on neurotoxicity are highlighted, with the hope of enhancing awareness in the public and calling for prevention and protective measures.
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Air pollution: A systematic review of its psychological, economic, and social effects.
TL;DR: This review is the first to systematically examine the psychological (affective, cognitive, behavioral), economic, and social effects of air pollution beyond its physiological and environmental effects.
References
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Mullen Scales of Early Learning
TL;DR: The Mullen Scales of Early Learning (MSEL) as mentioned in this paper includes five scales that provide information on cognitive and motor ability, including Gross Motor (0-33 months only), Visual Reception, Fine Motor, Expressive Language and Receptive Language.
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Ultrafine Particles Cross Cellular Membranes by Nonphagocytic Mechanisms in Lungs and in Cultured Cells
Marianne Geiser,Barbara Rothen-Rutishauser,Nadine Kapp,Samuel Schürch,Samuel Schürch,Wolfgang G. Kreyling,Holger Schulz,Manuela Semmler,Vinzenz Im Hof,Joachim Heyder,Peter Gehr +10 more
TL;DR: Inhaled ultrafine titanium dioxide particles were found on the luminal side of airways and alveoli, in all major lung tissue compartments and cells, and within capillaries, while particle uptake in vitro did not occur by any of the expected endocytic processes, but rather by diffusion or adhesive interactions.
Prevalence of Autism Spectrum Disorders: Autism and Developmental Disabilities Monitoring Network, United States, 2006. Morbidity and Mortality Weekly Report. Surveillance Summaries. Volume 58, Number SS-10.
TL;DR: The identified prevalence of ASDs in U.S. children aged 8 years was estimated through a systematic retrospective review of evaluation records in multiple sites participating in the Autism and Developmental Disabilities Monitoring (ADDM) Network and presence of an identified ASD was determined through a review of data abstracted from developmental evaluation records by trained clinician reviewers.
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Air pollution: mechanisms of neuroinflammation and CNS disease
TL;DR: Recent findings detailing the mechanisms through which air pollution reaches the brain and activates the resident innate immune response to become a chronic source of pro-inflammatory factors and ROS, culminating in CNS disease are summarized.