Traffic-related air pollution, particulate matter, and autism.
TLDR
Exposure to traffic-related air pollution, nitrogen dioxide, PM2.5, and PM10 during pregnancy and during the first year of life was associated with autism.Citations
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The Lancet Commission on pollution and health
Philip J. Landrigan,Richard Fuller,Nereus J R Acosta,Olusoji Adeyi,Robert G. Arnold,Niladri Basu,Abdoulaye Bibi Baldé,Roberto Bertollini,Stephan Bose-O'Reilly,Stephan Bose-O'Reilly,Jo Ivey Boufford,Patrick N. Breysse,Thomas C. Chiles,Chulabhorn Mahidol,Awa M Coll-Seck,Maureen L. Cropper,Julius N. Fobil,Valentin Fuster,Valentin Fuster,Michael Greenstone,Andy Haines,David Hanrahan,David J. Hunter,Mukesh Khare,Alan Krupnick,Bruce P. Lanphear,Bindu Lohani,Keith Martin,Karen V Mathiasen,Maureen A. McTeer,Christopher J L Murray,Johanita D Ndahimananjara,Frederica P. Perera,Janez Potočnik,Alexander S Preker,Alexander S Preker,Jairam Ramesh,Johan Rockström,Carlos Salinas,Leona D. Samson,Karti Sandilya,Peter D. Sly,Kirk R. Smith,Achim Steiner,Richard B. Stewart,William A. Suk,Onno C. P. van Schayck,Gautam N. Yadama,Kandeh K. Yumkella,Ma Zhong +49 more
TL;DR: This book is dedicated to the memory of those who have served in the armed forces and their families during the conflicts of the twentieth century.
Journal ArticleDOI
Neurobehavioural effects of developmental toxicity
TL;DR: To control the pandemic of developmental neurotoxicity, a global prevention strategy is proposed and chemicals in existing use and all new chemicals must therefore be tested for developmental neurotoxicants is proposed.
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The Changing Epidemiology of Autism Spectrum Disorders
Kristen Lyall,Lisa A. Croen,Julie L. Daniels,M. Daniele Fallin,Christine Ladd-Acosta,Brian K. Lee,Brian K. Lee,Bo Y. Park,Nathaniel W. Snyder,Diana Schendel,Diana Schendel,Heather E. Volk,Gayle C. Windham,Craig J. Newschaffer +13 more
TL;DR: Eviologic investigations focused on nongenetic factors have established advanced parental age and preterm birth as ASD risk factors, indicated that prenatal exposure to air pollution and short interpregnancy interval are potentialrisk factors, and suggested the need for further exploration of certain prenatal nutrients, metabolic conditions, and exposure to endocrine-disrupting chemicals.
Journal ArticleDOI
Identification, Evaluation, and Management of Children With Autism Spectrum Disorder.
TL;DR: This single clinical report updates the 2007 American Academy of Pediatrics clinical reports on the evaluation and treatment of ASD in one publication with an online table of contents and section view available to help the reader identify topic areas within the report.
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Pollution from Fossil-Fuel Combustion is the Leading Environmental Threat to Global Pediatric Health and Equity: Solutions Exist
TL;DR: The purpose of this commentary is to briefly review the data on the health impacts of fossil-fuel pollution, highlighting the neurodevelopmental impacts, and to briefly describe available means to achieve a low-carbon economy, and some examples of interventions that have benefited health and the economy.
References
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Journal ArticleDOI
Concentration and Size Distribution of Ultrafine Particles Near a Major Highway
TL;DR: Data showed that both atmospheric dispersion and coagulation contributed to the rapid decrease in particle number concentration and change in particle size distribution with increasing distance from the freeway.
Journal ArticleDOI
Study of ultrafine particles near a major highway with heavy-duty diesel traffic
TL;DR: In this article, the authors found that the relative concentration of CO, BC and particle number decreased exponentially and tracked each other well as one moves away from the freeway, and both atmospheric dispersion and coagulation appeared to contribute to the rapid decrease in particle number concentration and change in particle size distribution with increasing distance from a freeway.
Journal ArticleDOI
Innate immunity: the missing link in neuroprotection and neurodegeneration?
TL;DR: The long-term induction of the innate immune response and its transition to an adaptive form might be central to the pathophysiology and aetiology of neurodegenerative disorders.
DatasetDOI
Prevalence of Autism Spectrum Disorders --- Autism and Developmental Disabilities Monitoring Network, United States, 2006
TL;DR: The most recent data from the Autism and Developmental Disabilities Monitoring (ADDM) Network showed that the prevalence of autism spectrum disorders (ASDs) increased by 57% between 2002 and 2006 as mentioned in this paper, with an average prevalence of 9.0 per 1,000 population (95% confidence interval [CI] = 8.6-9.3).
Journal ArticleDOI
Elevated immune response in the brain of autistic patients.
Xiaohong Li,Abha Chauhan,Ashfaq M. Sheikh,Sangita P. Patil,Ved Chauhan,Xiu-Min Li,Lina Ji,Ted Brown,Mazhar Malik +8 more
TL;DR: ASD patients displayed an increased innate and adaptive immune response through the Th1 pathway, suggesting that localized brain inflammation and autoimmune disorder may be involved in the pathogenesis of ASD.