Transition from acute to chronic postsurgical pain: risk factors and protective factors
Joel Katz,Ze'ev Seltzer +1 more
TLDR
It is argued that a focus on the transition from acute to chronic pain may reveal important cues that will help to predict who will go on to develop chronic pain and who will not and how to identify the risk factors and protective factors that predict the course of recovery.Abstract:
Most patients who undergo surgery recover uneventfully and resume their normal daily activities within weeks. Nevertheless, chronic postsurgical pain develops in an alarming proportion of patients. The prevailing approach of focusing on established chronic pain implicitly assumes that information generated during the acute injury phase is not important to the subsequent development of chronic pain. However, a rarely appreciated fact is that every chronic pain was once acute. Here, we argue that a focus on the transition from acute to chronic pain may reveal important cues that will help us to predict who will go on to develop chronic pain and who will not. Unlike other injuries, surgery presents a unique set of circumstances in which the precise timing of the physical insult and ensuing pain are known in advance. This provides an opportunity, before surgery, to identify the risk factors and protective factors that predict the course of recovery. In this paper, the epidemiology of chronic postsurgical pain...read more
Citations
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Dissertation
Pain and Psychological Outcomes Following Traumatic Musculoskeletal Injury
TL;DR: Evidence from the eleven studies included in this review indicates that persistent pain is prevalent up to 84 months following traumatic injury, with wide variation among studies in pain intensity and pain incidence at each time point.
Journal ArticleDOI
Chronic Dry Eye Symptoms after LASIK: Parallels and Lessons to be Learned from other Persistent Post-Operative Pain Disorders:
Alexandra E. Levitt,Anat Galor,Anat Galor,Jayne S. Weiss,Elizabeth R. Felix,Elizabeth R. Felix,Eden R. Martin,Dennis Patin,Konstantinos D. Sarantopoulos,Roy C. Levitt +9 more
TL;DR: This review will focus on the known epidemiology of symptoms after LASIK and discuss mechanisms of persistent post-op pain due to nerve injury that may be relevant to patients, and the concept of genetic susceptibility to post-LASIK ocular surface pain is presented.
Journal ArticleDOI
Presurgical psychosocial predictors of acute postsurgical pain and quality of life in children undergoing major surgery.
Jennifer A. Rabbitts,Jennifer A. Rabbitts,Cornelius B. Groenewald,Cornelius B. Groenewald,G. Tai,Tonya M. Palermo,Tonya M. Palermo +6 more
TL;DR: In conclusion, child anxiety, parental pain catastrophizing, and sleep patterns are potentially modifiable factors that predict poor outcomes in children after major surgery.
Journal ArticleDOI
Prevalence and Predictive Factors of Chronic Postsurgical Pain and Poor Global Recovery 1 Year After Outpatient Surgery
Daisy M. N. Hoofwijk,Audrey A.A. Fiddelers,Madelon L. Peters,Björn Stessel,Alfons G.H. Kessels,Elbert A.J. Joosten,Hans-Fritz Gramke,Marco A. E. Marcus +7 more
TL;DR: Moderate to severe CPSP after outpatient surgery is common, and should not be underestimated, and patients at risk for developing CPSP can be identified during the preoperative phase.
Journal ArticleDOI
The search for novel analgesics: targets and mechanisms.
TL;DR: This review seeks to provide an overview of current thinking targeting pain biology, the use of preclinical models and the development of novel pain therapeutics, and the strengths and weaknesses of current development strategies for analgesics.
References
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