Open AccessJournal Article
[Two-photon laser scanning fluorescence microscopy].
About:
This article is published in Tanpakushitsu kakusan koso. Protein nucleic acid enzyme.The article was published on 2007-10-01 and is currently open access. It has received 1480 citations till now. The article focuses on the topics: Scanning confocal electron microscopy & Microscopy.read more
Citations
More filters
Journal ArticleDOI
Inorganic nanoparticle-based contrast agents for molecular imaging
TL;DR: Recent advances in the development of contrast agents based on inorganic NPs for molecular imaging are reviewed, and also touch on contrast enhancement, surface modification, tissue targeting, clearance and toxicity.
Journal ArticleDOI
In vivo calcium imaging of neural network function.
Werner Göbel,Fritjof Helmchen +1 more
TL;DR: Basic aspects of in vivo calcium imaging are discussed and recent developments that will help to uncover operating principles of neural circuits are highlighted.
Journal ArticleDOI
In Vivo Performance of Genetically Encoded Indicators of Neural Activity in Flies
Dierk F. Reiff,Alexandra Ihring,Giovanna Guerrero,Ehud Y. Isacoff,Maximillian Joesch,Junichi Nakai,Alexander Borst +6 more
TL;DR: A comparative in vivo analysis of 10 different genetically encoded calcium indicators, as well as the pH-sensitive synapto-pHluorin, finds that an expanded range of neural activity evoked fairly linear fluorescence changes and a corresponding linear increase in the signal-to-noise ratio (SNR).
Journal ArticleDOI
The development and application of femtosecond laser systems
TL;DR: Some background as well as recent progress in the development of femtosecond lasers are discussed together with a brief outline of a few representative emergent applications in biology and medicine that are underpinned by access to such sources.
Journal ArticleDOI
Single-spike detection in vitro and in vivo with a genetic Ca2+ sensor.
Damian J. Wallace,Stephan Meyer zum Alten Borgloh,Simone Astori,Ying Yang,Melanie Bausen,Sebastian Kügler,Amy E. Palmer,Roger Y. Tsien,Rolf Sprengel,Jason N. D. Kerr,Winfried Denk,Mazahir T. Hasan +11 more
TL;DR: In upper-layer cortical neurons, D3cpv, an improved fluorescent resonance energy transfer–based FCIP, using a recombinant adeno-associated virus results in expression sufficient to detect the Ca2+ transients that accompany single action potentials, with high reliability from in vivo recordings in living mice.