Open AccessJournal Article
[Two-photon laser scanning fluorescence microscopy].
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This article is published in Tanpakushitsu kakusan koso. Protein nucleic acid enzyme.The article was published on 2007-10-01 and is currently open access. It has received 1480 citations till now. The article focuses on the topics: Scanning confocal electron microscopy & Microscopy.read more
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Simultaneous cellular-resolution optical perturbation and imaging of place cell firing fields.
TL;DR: An optical method for simultaneous cellular-resolution stimulation and large-scale recording of neuronal activity in behaving mice is developed and manipulated task-modulated activity in individual hippocampal CA1 place cells during spatial navigation in a virtual reality environment, mimicking natural place-field activity, or 'biasing', to reveal subthreshold dynamics.
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TL;DR: How recent developments in nanoscale analysis tools and in the design and synthesis of nanomaterials have generated optical, electrical, and chemical methods that can readily be adapted for use in neuroscience is discussed.
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Major signal increase in fluorescence microscopy through dark-state relaxation
TL;DR: A substantial signal gain is reported in fluorescence microscopy by ensuring that transient molecular dark states with lifetimes >1 μs, such as the triplet state relax between two molecular absorption events.
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Optical sectioning microscopy with planar or structured illumination
TL;DR: This Review examines two techniques for optical sectioning based on planar illumination or structured illumination, particularly for applications involving high speeds, large fields of view or long-term imaging.
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Advances in Light Microscopy for Neuroscience
Brian A. Wilt,Laurie D. Burns,Eric Tatt Wei Ho,Kunal K. Ghosh,Eran A. Mukamel,Mark J. Schnitzer +5 more
TL;DR: Progress in Mouse genetic approaches permit mosaic and inducible fluorescence-labeling strategies, whereas intrinsic contrast mechanisms allow in vivo imaging of animals and humans without use of exogenous markers.