Journal ArticleDOI
Ultra-small fluorescent metal nanoclusters: Synthesis and biological applications
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TLDR
In this article, the authors summarize synthesis strategies of water-soluble fluorescent metal nanoclusters and their optical properties, highlight recent advances in their application for ultrasensitive biological detection and fluorescent biological imaging, and finally discuss current challenges for their potential biomedical applications.About:
This article is published in Nano Today.The article was published on 2011-08-01. It has received 1306 citations till now. The article focuses on the topics: Nanoclusters.read more
Citations
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Aluminum(III) triggered aggregation-induced emission of glutathione-capped copper nanoclusters as a fluorescent probe for creatinine.
TL;DR: Glutathione-capped copper nanoclusters (CuNCs) are presented that display aggregation-induced emission (AIE) and this feature was exploited for selective and sensitive quantification of creatinine (CRN) which is an important diagnostic parameter.
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DNA-hosted fluorescent gold nanoclusters: sequence-dependent formation.
TL;DR: The role of sequence is demonstrated in producing Au NCs that could serve as promising fluorescent nanoprobes in biosensing and DNA-hosted Au nanomaterials and can be modulated by the loop length.
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Functional biomedical hydrogels for in vivo imaging
TL;DR: In this review, current mainstreams of functional imaging hydrogels for in vivo tracking and their synthetic strategies are summarized and discussed and the future of functional Imaging hydrogel is envisioned based on the recent advances in imaging techniques.
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Synthesis of fluorescent gold nanodot-liposome hybrids for detection of phospholipase C and its inhibitor.
TL;DR: The practicality of using the 11-MUA-Au ND/Lip probe for the determination of PLC concentrations in breast cancer cells and nontumor cells is validated, revealing that the PLC activity in the first two is at least 1.5-fold higher than that in the third.
Journal ArticleDOI
Protein‐protected metal nanoclusters: An emerging ultra‐small nanozyme
TL;DR: Ultra-small nanozymes based on protein-protected MNCs are on the verge of attracting great interest across various disciplines and will stimulate research in the fields of nanotechnology and biology.
References
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Quantum Dots for Live Cells, in Vivo Imaging, and Diagnostics
Xavier Michalet,Fabien Pinaud,Laurent A. Bentolila,James M. Tsay,Sören Doose,J. Jack Li,Gobalakrishnan Sundaresan,Anna M. Wu,Sanjiv S. Gambhir,Sanjiv S. Gambhir,Shimon Weiss +10 more
TL;DR: The new generations of qdots have far-reaching potential for the study of intracellular processes at the single-molecule level, high-resolution cellular imaging, long-term in vivo observation of cell trafficking, tumor targeting, and diagnostics.
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Localized Surface Plasmon Resonance Spectroscopy and Sensing
TL;DR: This review describes recent fundamental spectroscopic studies that reveal key relationships governing the LSPR spectral location and its sensitivity to the local environment, including nanoparticle shape and size and introduces a new form of L SPR spectroscopy, involving the coupling between nanoparticle plasmon resonances and adsorbate molecular resonances.
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Luminescent Carbon Nanodots: Emergent Nanolights
Sheila N. Baker,Gary A. Baker +1 more
TL;DR: This Review summarize recent advances in the synthesis and characterization of C-dots and speculate on their future and discuss potential developments for their use in energy conversion/storage, bioimaging, drug delivery, sensors, diagnostics, and composites.
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The fluorescent toolbox for assessing protein location and function
TL;DR: The focus is on protein detection in live versus fixed cells: determination of protein expression, localization, activity state, and the possibility for combination of fluorescent light microscopy with electron microscopy.
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Water-Soluble Quantum Dots for Multiphoton Fluorescence Imaging in Vivo
Daniel R. Larson,Warren R. Zipfel,Rebecca M. Williams,S. W. Clark,Marcel P. Bruchez,Frank W. Wise,Watt W. Webb +6 more
TL;DR: This work characterized water-soluble cadmium selenide–zinc sulfide quantum dots for multiphoton imaging in live animals and found no evidence of blinking (fluorescence intermittency) in solution on nanosecond to millisecond time scales.