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Ultra-small fluorescent metal nanoclusters: Synthesis and biological applications
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In this article, the authors summarize synthesis strategies of water-soluble fluorescent metal nanoclusters and their optical properties, highlight recent advances in their application for ultrasensitive biological detection and fluorescent biological imaging, and finally discuss current challenges for their potential biomedical applications.About:
This article is published in Nano Today.The article was published on 2011-08-01. It has received 1306 citations till now. The article focuses on the topics: Nanoclusters.read more
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A Galvanic Replacement Route to Prepare Strongly Fluorescent and Highly Stable Gold Nanodots for Cellular Imaging
Chuanxi Wang,Yu Wang,Lin Xu,Xiaodong Shi,Xiangwei Li,Xiaowei Xu,Hongchen Sun,Bai Yang,Quan Lin +8 more
TL;DR: The application of galvanic replacement for the preparation of fluorescent GNDs is reported, using presynthesized and size-controlled Ag nanodots as templates, which show strong fluorescence with high stability and surface bioactivity and have potential application in biological labeling.
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Amphiphilic Polymeric Nanocarriers with Luminescent Gold Nanoclusters for Concurrent Bioimaging and Controlled Drug Release
TL;DR: The design of a theranostic nanocomposite capable of simultaneous targeting and imaging of the cancer cells is presented and in vivo studies show the selective accumulation of the FA‐conjugated nanocompositionite in tumor tissues by folate‐receptor‐mediated endocytosis.
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Catalytic Nanomaterials toward Atomic Levels for Biomedical Applications: From Metal Clusters to Single-Atom Catalysts.
TL;DR: In this paper, a review of the syntheses, characterizations, and catalytic mechanisms of metal clusters and single-atom catalysts is presented, with a focus on their biomedical applications including biosensing, antibacterial therapy, and cancer therapy.
Journal ArticleDOI
Facile sonochemical synthesis of pH-responsive copper nanoclusters for selective and sensitive detection of Pb2+ in living cells
TL;DR: CAL-27 cells are used as models to achieve potential application as probes for monitoring Pb(2+) in living cells and these fluorescent CuNCs could work as an alternative to conventional fluorescent probes for biolabeling, sensing and other applications.
Journal ArticleDOI
One-Pot Gram-Scale Synthesis of Nitrogen and Sulfur Embedded Organic Dots with Distinctive Fluorescence Behaviors in Free and Aggregated States
TL;DR: In this article, a new strategy for the gram-scale synthesis of highly blue fluorescent nitrogen and sulfur embedded organic dots through one-pot hydrothermal condensation of citric acid (CA) with cysteamine (Cys) at 200 °C was reported.
References
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Journal ArticleDOI
Quantum Dots for Live Cells, in Vivo Imaging, and Diagnostics
Xavier Michalet,Fabien Pinaud,Laurent A. Bentolila,James M. Tsay,Sören Doose,J. Jack Li,Gobalakrishnan Sundaresan,Anna M. Wu,Sanjiv S. Gambhir,Sanjiv S. Gambhir,Shimon Weiss +10 more
TL;DR: The new generations of qdots have far-reaching potential for the study of intracellular processes at the single-molecule level, high-resolution cellular imaging, long-term in vivo observation of cell trafficking, tumor targeting, and diagnostics.
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Localized Surface Plasmon Resonance Spectroscopy and Sensing
TL;DR: This review describes recent fundamental spectroscopic studies that reveal key relationships governing the LSPR spectral location and its sensitivity to the local environment, including nanoparticle shape and size and introduces a new form of L SPR spectroscopy, involving the coupling between nanoparticle plasmon resonances and adsorbate molecular resonances.
Journal ArticleDOI
Luminescent Carbon Nanodots: Emergent Nanolights
Sheila N. Baker,Gary A. Baker +1 more
TL;DR: This Review summarize recent advances in the synthesis and characterization of C-dots and speculate on their future and discuss potential developments for their use in energy conversion/storage, bioimaging, drug delivery, sensors, diagnostics, and composites.
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The fluorescent toolbox for assessing protein location and function
TL;DR: The focus is on protein detection in live versus fixed cells: determination of protein expression, localization, activity state, and the possibility for combination of fluorescent light microscopy with electron microscopy.
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Water-Soluble Quantum Dots for Multiphoton Fluorescence Imaging in Vivo
Daniel R. Larson,Warren R. Zipfel,Rebecca M. Williams,S. W. Clark,Marcel P. Bruchez,Frank W. Wise,Watt W. Webb +6 more
TL;DR: This work characterized water-soluble cadmium selenide–zinc sulfide quantum dots for multiphoton imaging in live animals and found no evidence of blinking (fluorescence intermittency) in solution on nanosecond to millisecond time scales.