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Ultra-small fluorescent metal nanoclusters: Synthesis and biological applications
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In this article, the authors summarize synthesis strategies of water-soluble fluorescent metal nanoclusters and their optical properties, highlight recent advances in their application for ultrasensitive biological detection and fluorescent biological imaging, and finally discuss current challenges for their potential biomedical applications.About:
This article is published in Nano Today.The article was published on 2011-08-01. It has received 1306 citations till now. The article focuses on the topics: Nanoclusters.read more
Citations
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Fabrication of folate bioconjugated near-infrared fluorescent silver nanoclusters for targeted in vitro and in vivo bioimaging
Yong Wang,Cong Dai,Xiu-Ping Yan +2 more
TL;DR: Thiolpolyethyleneimine stabilized silver nanoclusters with intense NIR fluorescence and chemical stability were fabricated in aqueous solution and bioconjugated with folate for targeted in vitro and in vivo bioimaging.
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Preparation of multi-coloured different sized fluorescent gold clusters from blue to NIR, structural analysis of the blue emitting Au7 cluster, and cell-imaging by the NIR gold cluster
Subhasish Roy,Abhishek Baral,Rameswar Bhattacharjee,Batakrishna Jana,Ayan Datta,Surajit Ghosh,Arindam Banerjee +6 more
TL;DR: Interestingly, it has been found that NIR emitting gold quantum cluster can easily be internalized into the adenocarcinomic human alveolar basal epithelial cell line (A549 cell line) and a MTT assay indicates that the NIR emitters show very low cytotoxicy to A549 cancer cells.
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Aggregation/assembly induced emission based on silk fibroin-templated fluorescent copper nanoclusters for “turn-on” detection of S2−
Guomei Zhang,Ruru Wang,Lihong Shi,Caihong Zhang,Yan Zhang,Ying Zhou,Chuan Dong,Gao Li,Shaomin Shuang +8 more
TL;DR: In this article, a simple one-pot green method synthesized fluorescent silk fibroin (SF) protected copper nanoclusters (CuNCs) possessing unique aggregation/assembly induced emission enhance (AIEE) characteristics with the assistance of sulfide ion in aqueous solution.
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Design and Utility of Metal/Metal Oxide Nanoparticles Mediated by Thioether End-Functionalized Polymeric Ligands
TL;DR: This review summarizes the synthetic methodologies and stability of nanoparticles and fluorescent nanoclusters of metals prepared by using thioether based ligands and highlights their applications in bio-imaging, sensing, drug delivery, magnetic resonance imaging (MRI), and catalysis.
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An easy synthesis of autofluorescent alloyed silver–gold nanoparticles
TL;DR: The alloyed silver-gold nanoparticles showed no significant cytotoxicity at a metal concentration of 5 μg mL-1 for 24 h, but were cytotoxic to some degree at 50 μgmL-1 at higher silver content.
References
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Journal ArticleDOI
Quantum Dots for Live Cells, in Vivo Imaging, and Diagnostics
Xavier Michalet,Fabien Pinaud,Laurent A. Bentolila,James M. Tsay,Sören Doose,J. Jack Li,Gobalakrishnan Sundaresan,Anna M. Wu,Sanjiv S. Gambhir,Sanjiv S. Gambhir,Shimon Weiss +10 more
TL;DR: The new generations of qdots have far-reaching potential for the study of intracellular processes at the single-molecule level, high-resolution cellular imaging, long-term in vivo observation of cell trafficking, tumor targeting, and diagnostics.
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Localized Surface Plasmon Resonance Spectroscopy and Sensing
TL;DR: This review describes recent fundamental spectroscopic studies that reveal key relationships governing the LSPR spectral location and its sensitivity to the local environment, including nanoparticle shape and size and introduces a new form of L SPR spectroscopy, involving the coupling between nanoparticle plasmon resonances and adsorbate molecular resonances.
Journal ArticleDOI
Luminescent Carbon Nanodots: Emergent Nanolights
Sheila N. Baker,Gary A. Baker +1 more
TL;DR: This Review summarize recent advances in the synthesis and characterization of C-dots and speculate on their future and discuss potential developments for their use in energy conversion/storage, bioimaging, drug delivery, sensors, diagnostics, and composites.
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The fluorescent toolbox for assessing protein location and function
TL;DR: The focus is on protein detection in live versus fixed cells: determination of protein expression, localization, activity state, and the possibility for combination of fluorescent light microscopy with electron microscopy.
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Water-Soluble Quantum Dots for Multiphoton Fluorescence Imaging in Vivo
Daniel R. Larson,Warren R. Zipfel,Rebecca M. Williams,S. W. Clark,Marcel P. Bruchez,Frank W. Wise,Watt W. Webb +6 more
TL;DR: This work characterized water-soluble cadmium selenide–zinc sulfide quantum dots for multiphoton imaging in live animals and found no evidence of blinking (fluorescence intermittency) in solution on nanosecond to millisecond time scales.