Journal ArticleDOI
Ultra-small fluorescent metal nanoclusters: Synthesis and biological applications
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TLDR
In this article, the authors summarize synthesis strategies of water-soluble fluorescent metal nanoclusters and their optical properties, highlight recent advances in their application for ultrasensitive biological detection and fluorescent biological imaging, and finally discuss current challenges for their potential biomedical applications.About:
This article is published in Nano Today.The article was published on 2011-08-01. It has received 1306 citations till now. The article focuses on the topics: Nanoclusters.read more
Citations
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Label-free detection of sulfide ions based on fluorescence quenching of unmodified core–shell Au@Ag nanoclusters
TL;DR: A simple label-free method for the detection of S2− ions with high selectivity and sensitivity by using fluorescent core-shell Au@Ag NCs in aqueous media was proposed in this paper.
Journal ArticleDOI
Silver Nanoclusters with Specific Ion Recognition Modulated by Ligand Passivation toward Fluorimetric and Colorimetric Copper Analysis and Biological Imaging
Zongzhao Sun,Shuying Li,Yao Jiang,Yuchun Qiao,Liyan Zhang,Lulu Xu,Jinghui Liu,Wei Qi,Hua Wang,Hua Wang +9 more
TL;DR: This study indicates that the use of functional ligands like GSH could not only modulate the specific ion recognition of AgNCs, but also endow them the high aqueous stability and powerful red fluorescence towards the wide applications for ion sensing and biological imaging in the complicated media like blood.
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One-step aqueous synthesis of fluorescent copper nanoclusters by direct metal reduction.
Mónica Fernández-Ujados,Laura Trapiella-Alfonso,José M. Costa-Fernández,Rosario Pereiro,Alfredo Sanz-Medel +4 more
TL;DR: The synthesized CuNCs obtained offer long-term stability under a broad range of chemical conditions and high photostability, keeping their fluorescence emission intact after more than 2 h of daylight and UV-light exposition, being promising fluorescent nanoprobes for further developments including (bio)applications.
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Metal nanocluster light-emitting devices with suppressed parasitic emission and improved efficiency: exploring the impact of photophysical properties
Tae-Wook Koh,Anna M. Hiszpanski,Melda Sezen,A. Naim,Tal Galfsky,A. Trivedi,Yueh-Lin Loo,Vinod M. Menon,Barry P. Rand +8 more
TL;DR: It is demonstrated that by varying the sizes of nanoclusters, the electroluminescence spectrum of the device can be tuned to the infrared emission, indicating the possibility of exploiting metal nanocluster emitters for use over a wide spectral range.
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Exploring luminescence-based temperature sensing using protein-passivated gold nanoclusters
TL;DR: It is found that these bio-passivated AuNCs show pronounced hysteresis upon thermal cycling, which can be eliminated by several strategies, including sol-gel coating and thermal denaturation of the biomolecular template.
References
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Quantum Dots for Live Cells, in Vivo Imaging, and Diagnostics
Xavier Michalet,Fabien Pinaud,Laurent A. Bentolila,James M. Tsay,Sören Doose,J. Jack Li,Gobalakrishnan Sundaresan,Anna M. Wu,Sanjiv S. Gambhir,Sanjiv S. Gambhir,Shimon Weiss +10 more
TL;DR: The new generations of qdots have far-reaching potential for the study of intracellular processes at the single-molecule level, high-resolution cellular imaging, long-term in vivo observation of cell trafficking, tumor targeting, and diagnostics.
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Localized Surface Plasmon Resonance Spectroscopy and Sensing
TL;DR: This review describes recent fundamental spectroscopic studies that reveal key relationships governing the LSPR spectral location and its sensitivity to the local environment, including nanoparticle shape and size and introduces a new form of L SPR spectroscopy, involving the coupling between nanoparticle plasmon resonances and adsorbate molecular resonances.
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Luminescent Carbon Nanodots: Emergent Nanolights
Sheila N. Baker,Gary A. Baker +1 more
TL;DR: This Review summarize recent advances in the synthesis and characterization of C-dots and speculate on their future and discuss potential developments for their use in energy conversion/storage, bioimaging, drug delivery, sensors, diagnostics, and composites.
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The fluorescent toolbox for assessing protein location and function
TL;DR: The focus is on protein detection in live versus fixed cells: determination of protein expression, localization, activity state, and the possibility for combination of fluorescent light microscopy with electron microscopy.
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Water-Soluble Quantum Dots for Multiphoton Fluorescence Imaging in Vivo
Daniel R. Larson,Warren R. Zipfel,Rebecca M. Williams,S. W. Clark,Marcel P. Bruchez,Frank W. Wise,Watt W. Webb +6 more
TL;DR: This work characterized water-soluble cadmium selenide–zinc sulfide quantum dots for multiphoton imaging in live animals and found no evidence of blinking (fluorescence intermittency) in solution on nanosecond to millisecond time scales.