Journal ArticleDOI
Ultra-small fluorescent metal nanoclusters: Synthesis and biological applications
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In this article, the authors summarize synthesis strategies of water-soluble fluorescent metal nanoclusters and their optical properties, highlight recent advances in their application for ultrasensitive biological detection and fluorescent biological imaging, and finally discuss current challenges for their potential biomedical applications.About:
This article is published in Nano Today.The article was published on 2011-08-01. It has received 1306 citations till now. The article focuses on the topics: Nanoclusters.read more
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Revisiting the conformational state of albumin conjugated to gold nanoclusters: A self-assembly pathway to giant superstructures unraveled.
Michał Kluz,Hanna Nieznanska,Robert Dec,Robert Dec,Igor Dzięcielewski,Bartosz Niżyński,Grzegorz Ścibisz,Wojciech Puławski,Grzegorz Staszczak,Ewelina Klein,Julita Smalc-Koziorowska,Wojciech Dzwolak,Wojciech Dzwolak +12 more
TL;DR: The newly discovered self-association pathway appears to be specifically accessible to protein molecules with a certain restriction on structural dynamics which in the case of BSA-AuNC arises from binding to metal nanoclusters.
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Understanding the Effect of Single Cysteine Mutations on Gold Nanoclusters as Studied by Spectroscopy and Density Functional Theory Modeling
Sayantani Chall,Soumya Sundar Mati,Indranee Das,Amrita Kundu,Goutam De,Krishnananda Chattopadhyay +5 more
TL;DR: The experimental results show that cysteine residues positioned in two different regions of the protein induce varying electronic states of the nanoclusters depending on the surrounding amino acids.
Journal ArticleDOI
Self-assembled ultrasmall silver nanoclusters on liposome for topical antimicrobial delivery.
TL;DR: In this article, a core-shell structured Ultrasmall silver nanocluster (Ag NC) based nanocomposite was synthesized through the encapsulation of Ag NCs in the phosphatidylcholine liposomes.
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Specific recognition of DNA bulge sites by in situ grown fluorescent Ag nanoclusters with high selectivity.
TL;DR: The bulge site in the DNA duplex can be used to selectively grow fluorescent silver nanoclusters (Ag NCs) and the strong dependence of the fluorescent Ag NCs' formation on the bases surrounding the Bulge site is successfully used to identify the bulge environment near the codon 177 of cancer suppression gene p53.
Journal ArticleDOI
Core-in-cage structure regulated properties of ultra-small gold nanoparticles
Nirmal Goswami,Richard Bright,Richard Bright,Rahul Madathiparambil Visalakshan,Bhabananda Biswas,Peter S. Zilm,Krasimir Vasilev +6 more
TL;DR: In this article, a series of ultra-small gold nanoparticles (AuNPs; diameter below 3 nm) with different core-in-cage structures were studied and the density of metallic core and cage containing Au(I)−thiolate motifs, as well as cage rigidity were identified as crucial factors that can significantly modulate the optical and biological properties of these AuNPs.
References
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Quantum Dots for Live Cells, in Vivo Imaging, and Diagnostics
Xavier Michalet,Fabien Pinaud,Laurent A. Bentolila,James M. Tsay,Sören Doose,J. Jack Li,Gobalakrishnan Sundaresan,Anna M. Wu,Sanjiv S. Gambhir,Sanjiv S. Gambhir,Shimon Weiss +10 more
TL;DR: The new generations of qdots have far-reaching potential for the study of intracellular processes at the single-molecule level, high-resolution cellular imaging, long-term in vivo observation of cell trafficking, tumor targeting, and diagnostics.
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Localized Surface Plasmon Resonance Spectroscopy and Sensing
TL;DR: This review describes recent fundamental spectroscopic studies that reveal key relationships governing the LSPR spectral location and its sensitivity to the local environment, including nanoparticle shape and size and introduces a new form of L SPR spectroscopy, involving the coupling between nanoparticle plasmon resonances and adsorbate molecular resonances.
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Luminescent Carbon Nanodots: Emergent Nanolights
Sheila N. Baker,Gary A. Baker +1 more
TL;DR: This Review summarize recent advances in the synthesis and characterization of C-dots and speculate on their future and discuss potential developments for their use in energy conversion/storage, bioimaging, drug delivery, sensors, diagnostics, and composites.
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The fluorescent toolbox for assessing protein location and function
TL;DR: The focus is on protein detection in live versus fixed cells: determination of protein expression, localization, activity state, and the possibility for combination of fluorescent light microscopy with electron microscopy.
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Water-Soluble Quantum Dots for Multiphoton Fluorescence Imaging in Vivo
Daniel R. Larson,Warren R. Zipfel,Rebecca M. Williams,S. W. Clark,Marcel P. Bruchez,Frank W. Wise,Watt W. Webb +6 more
TL;DR: This work characterized water-soluble cadmium selenide–zinc sulfide quantum dots for multiphoton imaging in live animals and found no evidence of blinking (fluorescence intermittency) in solution on nanosecond to millisecond time scales.