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Ultra-small fluorescent metal nanoclusters: Synthesis and biological applications
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In this article, the authors summarize synthesis strategies of water-soluble fluorescent metal nanoclusters and their optical properties, highlight recent advances in their application for ultrasensitive biological detection and fluorescent biological imaging, and finally discuss current challenges for their potential biomedical applications.About:
This article is published in Nano Today.The article was published on 2011-08-01. It has received 1306 citations till now. The article focuses on the topics: Nanoclusters.read more
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Recent Advances in Nanomaterial Probes for Optical Biothiol Sensing: A Review
TL;DR: The determination of biological aminothiols (mainly cysteine, homocysteine and glutathione) is an important tool in the clinical diagnosis of many disorders and diseases as mentioned in this paper.
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Gold nanoparticle-enhanced near infrared fluorescent nanocomposites for targeted bio-imaging
TL;DR: The results show that the developed nanocomposites can effectively enhance the NIR fluorescence signal of the Ag2S NCs and have potential applications in distinguishing folate receptor-positive cancer cells from normal cells.
Journal ArticleDOI
Electrochemical synthesis of silver nanoclusters on electrochemiluminescent resonance energy transfer amplification platform for Apo-A1 detection.
TL;DR: A novel electrochemiluminescence resonance energy transfer (ERET) strategy between in situ electrogenerated silver nanoclusters (AgNCs) as the donor and Ru(bpy)2(5-NH2-1,10-phen)Cl2 (Ru(II)) as the acceptor was reported, which was applied for the construction of a ultrasensitive immunosensor for the determination of apolipoprotein-A1 (Apo-A 1).
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Microwave-assisted one-step rapid synthesis of near-infrared gold nanoclusters for NIRF/CT dual-modal bioimaging
TL;DR: A one-step microwave-assisted approach to synthesize lysozyme-capped gold nanoclusters (Lys-Au NCs) rapidly instead of traditional conditions provided significant contrast signals in both NIRF (near-infrared fluorescence) and CT (X-ray computed tomography) in vivo imaging.
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Self-assembly of hybridized ligands on gold nanodots: tunable photoluminescence and sensing of nitrite
TL;DR: Highly photoluminescent gold nanodots (Au NDs) via etching and co-deposition of hybridized ligands [11-mercaptoundecanol (11-MU) and its complexes with amphiphilic ligands] on gold nanoparticles (∼3 nm) have been prepared and employed for the detection of nitrite based on the analyte-induced photolUMinescence quenching.
References
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Journal ArticleDOI
Quantum Dots for Live Cells, in Vivo Imaging, and Diagnostics
Xavier Michalet,Fabien Pinaud,Laurent A. Bentolila,James M. Tsay,Sören Doose,J. Jack Li,Gobalakrishnan Sundaresan,Anna M. Wu,Sanjiv S. Gambhir,Sanjiv S. Gambhir,Shimon Weiss +10 more
TL;DR: The new generations of qdots have far-reaching potential for the study of intracellular processes at the single-molecule level, high-resolution cellular imaging, long-term in vivo observation of cell trafficking, tumor targeting, and diagnostics.
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Localized Surface Plasmon Resonance Spectroscopy and Sensing
TL;DR: This review describes recent fundamental spectroscopic studies that reveal key relationships governing the LSPR spectral location and its sensitivity to the local environment, including nanoparticle shape and size and introduces a new form of L SPR spectroscopy, involving the coupling between nanoparticle plasmon resonances and adsorbate molecular resonances.
Journal ArticleDOI
Luminescent Carbon Nanodots: Emergent Nanolights
Sheila N. Baker,Gary A. Baker +1 more
TL;DR: This Review summarize recent advances in the synthesis and characterization of C-dots and speculate on their future and discuss potential developments for their use in energy conversion/storage, bioimaging, drug delivery, sensors, diagnostics, and composites.
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The fluorescent toolbox for assessing protein location and function
TL;DR: The focus is on protein detection in live versus fixed cells: determination of protein expression, localization, activity state, and the possibility for combination of fluorescent light microscopy with electron microscopy.
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Water-Soluble Quantum Dots for Multiphoton Fluorescence Imaging in Vivo
Daniel R. Larson,Warren R. Zipfel,Rebecca M. Williams,S. W. Clark,Marcel P. Bruchez,Frank W. Wise,Watt W. Webb +6 more
TL;DR: This work characterized water-soluble cadmium selenide–zinc sulfide quantum dots for multiphoton imaging in live animals and found no evidence of blinking (fluorescence intermittency) in solution on nanosecond to millisecond time scales.