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Ultra-small fluorescent metal nanoclusters: Synthesis and biological applications
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In this article, the authors summarize synthesis strategies of water-soluble fluorescent metal nanoclusters and their optical properties, highlight recent advances in their application for ultrasensitive biological detection and fluorescent biological imaging, and finally discuss current challenges for their potential biomedical applications.About:
This article is published in Nano Today.The article was published on 2011-08-01. It has received 1306 citations till now. The article focuses on the topics: Nanoclusters.read more
Citations
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Polyethylenimine-capped silver nanoclusters as fluorescent sensors for the rapid detection of ellagic acid in cosmetics
TL;DR: Polyethylenimine-capped silver nanoclusters (PEI-AgNCs) are being developed as fluorescent sensors because of their high fluorescence, excellent photostability and large Stokes shift and they have also been applied in the detection of a cosmetics containing ellagic acid.
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Glutathione-Mediated Cu(I)/Cu(II) Complexes: Valence-Dependent Effects on Clearance and In Vivo Imaging Application.
TL;DR: It is found that Cu(I)-GSH complex revealed much more efficient renal clearance and remarkably lower liver accumulation than that of their oxidation states, which could be due to strong protein binding of partial forms of Cu(II)-GSSG complex.
Journal ArticleDOI
Which Amino Acids are Capable of Nucleating Fluorescent Silver Clusters in Proteins
Tomash S. Sych,Andrey A. Buglak,Zakhar V. Reveguk,Vladimir A. Pomogaev,Vladimir A. Pomogaev,Ruslan R. Ramazanov,A. I. Kononov +6 more
TL;DR: In this article, the Gibbs free energies of the complexes formed between Ag+ ions, Ag atoms, and two-atom Ag clusters with the amino acids' various functional groups were calculated.
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Live-cell imaging of biothiols via thiol/disulfide exchange to trigger the photoinduced electron transfer of gold-nanodot sensor.
TL;DR: The surface-functionalized Au8-cluster has significant promise for use as an efficient nanoprobe for intracellular fluorescence imaging of biothiols including protein thiols in living cells whereas other nanoparticle-based fluorescent probes cannot.
Journal ArticleDOI
Surface Engineering of Gold Nanoclusters Protected with 11-Mercaptoundecanoic Acid for Photoluminescence Sensing
Lin Zhu,Yuan Zeng,Melissa Teubner,Melissa Teubner,Benjamin Grimm-Lebsanft,Anna R. Ziefuß,Christoph Rehbock,Michael Rübhausen,Stephan Barcikowski,Wolfgang J. Parak,Indranath Chakraborty +10 more
TL;DR: In this paper, the photoluminescence properties of water-soluble, structurally protected gold nanoclusters were investigated as a model to understand the photophotonicity properties.
References
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Journal ArticleDOI
Quantum Dots for Live Cells, in Vivo Imaging, and Diagnostics
Xavier Michalet,Fabien Pinaud,Laurent A. Bentolila,James M. Tsay,Sören Doose,J. Jack Li,Gobalakrishnan Sundaresan,Anna M. Wu,Sanjiv S. Gambhir,Sanjiv S. Gambhir,Shimon Weiss +10 more
TL;DR: The new generations of qdots have far-reaching potential for the study of intracellular processes at the single-molecule level, high-resolution cellular imaging, long-term in vivo observation of cell trafficking, tumor targeting, and diagnostics.
Journal ArticleDOI
Localized Surface Plasmon Resonance Spectroscopy and Sensing
TL;DR: This review describes recent fundamental spectroscopic studies that reveal key relationships governing the LSPR spectral location and its sensitivity to the local environment, including nanoparticle shape and size and introduces a new form of L SPR spectroscopy, involving the coupling between nanoparticle plasmon resonances and adsorbate molecular resonances.
Journal ArticleDOI
Luminescent Carbon Nanodots: Emergent Nanolights
Sheila N. Baker,Gary A. Baker +1 more
TL;DR: This Review summarize recent advances in the synthesis and characterization of C-dots and speculate on their future and discuss potential developments for their use in energy conversion/storage, bioimaging, drug delivery, sensors, diagnostics, and composites.
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The fluorescent toolbox for assessing protein location and function
TL;DR: The focus is on protein detection in live versus fixed cells: determination of protein expression, localization, activity state, and the possibility for combination of fluorescent light microscopy with electron microscopy.
Journal ArticleDOI
Water-Soluble Quantum Dots for Multiphoton Fluorescence Imaging in Vivo
Daniel R. Larson,Warren R. Zipfel,Rebecca M. Williams,S. W. Clark,Marcel P. Bruchez,Frank W. Wise,Watt W. Webb +6 more
TL;DR: This work characterized water-soluble cadmium selenide–zinc sulfide quantum dots for multiphoton imaging in live animals and found no evidence of blinking (fluorescence intermittency) in solution on nanosecond to millisecond time scales.