Wearable and Implantable Devices for Cardiovascular Healthcare: from Monitoring to Therapy Based on Flexible and Stretchable Electronics
TLDR
Recent advances in wearable and implantable devices based on flexible and stretchable electronics for cardiovascular monitoring and therapy and device‐assisted tissue engineering therapy is discussed.Abstract:
Cardiovascular disease is the leading cause of death and has dramatically increased in recent years. Continuous cardiac monitoring is particularly important for early diagnosis and prevention, and flexible and stretchable electronic devices have emerged as effective tools for this purpose. Their thin, soft, and deformable features allow intimate and long-term integration with biotissues, which enables continuous, high-fidelity, and sometimes large-area cardiac monitoring on the skin and/or heart surface. In addition to monitoring, intimate contact is also crucial for high-precision therapies. Combined with tissue engineering, soft bioelectronics have also demonstrated the capability to repair damaged cardiac tissues. This review highlights the recent advances in wearable and implantable devices based on flexible and stretchable electronics for cardiovascular monitoring and therapy. First, wearable/implantable soft bioelectronics for cardiovascular monitoring (e.g., the electrocardiogram, blood pressure, and oxygen saturation level) are reviewed. Then, advances in cardiovascular therapy based on soft bioelectronics (e.g., mesh pacing, ablation, robotic sleeves, and electronic stents) are discussed. Finally, device-assisted tissue engineering therapy (e.g., functional electronic scaffolds and in vitro cardiac platforms) is discussed.read more
Citations
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Nanowired three-dimensional cardiac patches
Tal Dvir,Tal Dvir,Brian P. Timko,Brian P. Timko,Mark D. Brigham,Shreesh R. Naik,Sandeep S. Karajanagi,Sandeep S. Karajanagi,Oren Levy,Oren Levy,Hongwei Jin,Kevin Kit Parker,Robert Langer,Daniel S. Kohane +13 more
TL;DR: Incorporating gold nanowires into scaffolds used to create heart patches can improve electrical communication between cells and enhance the growth of tissues as discussed by the authors, which can improve the electrical communication among cells.
Journal ArticleDOI
Multifunctional materials for implantable and wearable photonic healthcare devices.
Geon-Hui Lee,Geon-Hui Lee,Hanul Moon,Hanul Moon,Hyemin Kim,Gae Hwang Lee,Gae Hwang Lee,Woosung Kwon,Seunghyup Yoo,David Myung,Seok Hyun Yun,Zhenan Bao,Sei Kwang Hahn,Sei Kwang Hahn +13 more
TL;DR: This Review describes emerging multifunctional materials critical to the advent of next-generation implantable and wearable photonic healthcare devices and discusses the path for their clinical translation, along with the future research directions for the field, particularly regarding mobile healthcare and personalized medicine.
Journal ArticleDOI
Superhydrophobic and breathable smart MXene-based textile for multifunctional wearable sensing electronics
Junchen Luo,Shijie Gao,Hui Luo,Ling Wang,Xuewu Huang,Zheng Guo,Xuejun Lai,Liwei Lin,Robert K.Y. Li,Jiefeng Gao +9 more
TL;DR: Wang et al. as mentioned in this paper fabricated a waterproof and breathable smart textile by construction of a multiple core-shell structure, i.e., MXene decoration onto the polydopamine (PDA) modified elastic textile followed by polydimethylsiloxane (PDMS) coating.
Journal ArticleDOI
Stretchable Electronics Based on PDMS Substrates.
TL;DR: The strategies for fabricating stretchable electronics on PDMS substrates are summarized, and the influence of the physical and chemical properties of PDMS, including surface chemical status, physical modulus, geometric structures, and self-healing properties, on the performance of stretchable Electronics is discussed.
Journal ArticleDOI
Disruptive, Soft, Wearable Sensors.
Yunzhi Ling,Yunzhi Ling,Tiance An,Tiance An,Lim Wei Yap,Lim Wei Yap,Bowen Zhu,Bowen Zhu,Shu Gong,Shu Gong,Wenlong Cheng,Wenlong Cheng +11 more
TL;DR: The state‐of‐the‐art progress made in the key phases for future wearable technology, namely, wear → sense → communicate → analyze → interpret → decide, is summarized.
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