Journal ArticleDOI
World Gastroenterology Organisation Global Guidelines: GERD Global Perspective on Gastroesophageal Reflux Disease.
Richard H. Hunt,David Armstrong,Peter H. Katelaris,Mary Afihene,Abate Bane,Shobna Bhatia,Minhu Chen,Myung Gyu Choi,Angelita Cristine de Melo,Kwong Ming Fock,Alex Ford,Michio Hongo,Aamir G. Khan,Leonid B. Lazebnik,Greger Lindberg,Maribel Lizarzábal,Thein Myint,Joaquim Prado P Moraes-Filho,Graciela Salis,Jaw-Town Lin,Raj Vaidya,Abdelmounen Abdo,Anton LeMair +22 more
Reads0
Chats0
TLDR
A century ago, Elie Metchnikoff postulated that lactic acid bacteria offered health benefits capable of promoting longevity and suggested that “intestinal autoint” bacteria should be studied.Abstract:
PROBIOTICS—THE CONCEPTHistory and DefinitionsA century ago, Elie Metchnikoff (a Russian scientist, Nobel laureate, and professor at the Pasteur Institute in Paris) postulated that lactic acid bacteria (LAB) offered health benefits capable of promoting longevity. He suggested that “intestinal autointread more
Citations
More filters
Journal ArticleDOI
Evolution of Image-Guided Liver Surgery: Transition from Open to Laparoscopic Procedures
T. Peter Kingham,Shiva Jayaraman,Logan W. Clements,Michael A. Scherer,James D. Stefansic,William R. Jarnagin +5 more
TL;DR: improving intraoperative image guidance can help expand the ability to perform both laparoscopic and open liver surgeries, as well as assist in overcoming some of the obstacles to minimally invasive liver procedures.
Journal ArticleDOI
Analysis of postmarketing safety data for proton-pump inhibitors reveals increased propensity for renal injury, electrolyte abnormalities, and nephrolithiasis.
TL;DR: Evidence of kidney injury and electrolyte imbalances in an alarming number of patients taking PPIs is provided and differences between specific PPIs are assessed and significant electrolyte and renal abnormalities for each individual drug with varying magnitudes are observed.
Journal ArticleDOI
Histone acetyltransferase PCAF accelerates apoptosis by repressing a GLI1/BCL2/BAX axis in hepatocellular carcinoma
TL;DR: The results show that PCAF can induce cell apoptosis by modulating a GLI1/Bcl-2/BAX axis that in turn suppresses HCC progression, and suggest that 5-FU may exert a stronger anti-tumor effect in patients with PCAF expression in HCC tumors.
Journal ArticleDOI
Risk factors for hepatocellular carcinoma in India.
TL;DR: Prevention of viral infection by universal vaccination against hepatitis virus, HCC surveillance program, preventing alcoholic liver diseases, fungal contamination of grains and ground crops to prevent basically Aflatoxin exposure are important measures to prevent liver diseases and HCC among those at risk.
Journal ArticleDOI
Increased Risk for Obesity and Diabetes with Neurodegeneration in Developing Countries
TL;DR: In this paper, the authors suggest that access to high calorie diets in urban areas down regulate liver nuclear receptors that are responsible for glucose, lipid and toxicological sensing and interrupt the metabolism of xenobiotics that become toxic to various tissues such as the pancreas, heart, kidney, brain and liver.
References
More filters
Journal ArticleDOI
The Montreal Definition and Classification of Gastroesophageal Reflux Disease: A Global Evidence-Based Consensus
TL;DR: Novel aspects of the new definition include a patient-centered approach that is independent of endoscopic findings, subclassification of the disease into discrete syndrome, and the recognition of laryngitis, cough, asthma, and dental erosions as possible GERD syndromes.
Journal ArticleDOI
Management of Helicobacter pylori infection—the Maastricht IV/ Florence Consensus Report
Peter Malfertheiner,Francis Mégraud,John Atherton,Anthony T. R. Axon,Franco Bazzoli,Gian Franco Gensini,Javier P. Gisbert,David Y. Graham,Ernst J. Kuipers +8 more
TL;DR: In this 4th edition of the Maastricht consensus report aspects related to the clinical role of H pylori were looked at again in 2010, with recommendations to guide doctors involved in the management of this infection associated with various clinical conditions.
Journal ArticleDOI
Gluten, major histocompatibility complex, and the small intestine: A molecular and immunobiologic approach to the spectrum of gluten sensitivity (‘celiac sprue’)
TL;DR: The nature and basis of nonresponsive celiac sprue require more thoughtful initiatives to elucidate the immunologic mechanism(s) of unresponsiveness and evaluate possible means of reversal.