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Ajay Pillai
Researcher at National Institutes of Health
Publications - 36
Citations - 1262
Ajay Pillai is an academic researcher from National Institutes of Health. The author has contributed to research in topics: Plasmodium falciparum & Gene. The author has an hindex of 14, co-authored 35 publications receiving 1033 citations. Previous affiliations of Ajay Pillai include Dumfries and Galloway Royal Infirmary.
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Journal ArticleDOI
The Library of Integrated Network-Based Cellular Signatures NIH Program: System-Level Cataloging of Human Cells Response to Perturbations
Alexandra B Keenan,Sherry L. Jenkins,Kathleen M. Jagodnik,Simon Koplev,Edward He,Denis Torre,Zichen Wang,Anders B. Dohlman,Moshe C. Silverstein,Alexander Lachmann,Maxim V. Kuleshov,Avi Ma'ayan,Vasileios Stathias,Raymond Terryn,Daniel J. Cooper,Michele Forlin,Amar Koleti,Dusica Vidovic,Caty Chung,Stephan C. Schürer,Jouzas Vasiliauskas,Marcin Pilarczyk,Behrouz Shamsaei,Mehdi Fazel,Yan Ren,Wen Niu,Nicholas A. Clark,Shana White,Naim Al Mahi,Lixia Zhang,Michal Kouril,John F. Reichard,Siva Sivaganesan,Mario Medvedovic,Jaroslaw Meller,Rick J. Koch,Marc R. Birtwistle,Ravi Iyengar,Eric A. Sobie,Evren U. Azeloglu,Julia A. Kaye,Jeannette Osterloh,Kelly Haston,Jaslin Kalra,Steve Finkbiener,Jonathan Z. Li,Pamela Milani,Miriam Adam,Renan Escalante-Chong,Karen Sachs,Alexander LeNail,Divya Ramamoorthy,Ernest Fraenkel,Gavin Daigle,Uzma Hussain,Alyssa Coye,Jeffrey D. Rothstein,Dhruv Sareen,Loren Ornelas,Maria G. Banuelos,Berhan Mandefro,Ritchie Ho,Clive N. Svendsen,Ryan G. Lim,Jennifer Stocksdale,Malcolm Casale,Terri G. Thompson,Jie Wu,Leslie M. Thompson,Victoria Dardov,Vidya Venkatraman,Andrea Matlock,Jennifer E. Van Eyk,Jacob D. Jaffe,Malvina Papanastasiou,Aravind Subramanian,Todd R. Golub,Sean D. Erickson,Mohammad Fallahi-Sichani,Marc Hafner,Nathanael S. Gray,Jia-Ren Lin,Caitlin E. Mills,Jeremy L. Muhlich,Mario Niepel,Caroline E. Shamu,Elizabeth H. Williams,David Wrobel,Peter K. Sorger,Laura M. Heiser,Joe W. Gray,James E. Korkola,Gordon B. Mills,Mark A. LaBarge,Mark A. LaBarge,Heidi S. Feiler,Mark A. Dane,Elmar Bucher,Michel Nederlof,Damir Sudar,Sean M. Gross,David Kilburn,Rebecca Smith,Kaylyn Devlin,Ron Margolis,Leslie Derr,Albert Lee,Ajay Pillai +107 more
TL;DR: The LINCS program focuses on cellular physiology shared among tissues and cell types relevant to an array of diseases, including cancer, heart disease, and neurodegenerative disorders.
Journal ArticleDOI
Malaria Parasite clag3 Genes Determine Channel-Mediated Nutrient Uptake by Infected Red Blood Cells
Wang Nguitragool,Abdullah A. B. Bokhari,Ajay Pillai,Kempaiah Rayavara,Paresh Sharma,Brad Turpin,L. Aravind,Sanjay A. Desai +7 more
TL;DR: DNA transfection and in vitro selections indicate that PSAC-inhibitor interactions are encoded by two clag3 genes previously assumed to function in cytoadherence, which are conserved in plasmodia, exhibit expression switching, and encode an integral protein on the host membrane, as predicted by functional studies.
Journal ArticleDOI
Data Portal for the Library of Integrated Network-based Cellular Signatures (LINCS) program: integrated access to diverse large-scale cellular perturbation response data.
Amar Koleti,Amar Koleti,Raymond Terryn,Raymond Terryn,Vasileios Stathias,Vasileios Stathias,Caty Chung,Caty Chung,Daniel J. Cooper,Daniel J. Cooper,John Paul Turner,John Paul Turner,Dusica Vidovic,Dusica Vidovic,Michele Forlin,Michele Forlin,Tanya T. Kelley,Tanya T. Kelley,Alessandro D'Urso,Alessandro D'Urso,Bryce K. Allen,Bryce K. Allen,Denis Torre,Kathleen M. Jagodnik,Lily Wang,Sherry L. Jenkins,Christopher C. Mader,Christopher C. Mader,Wen Niu,Wen Niu,Mehdi Fazel,Mehdi Fazel,Naim Al Mahi,Naim Al Mahi,Marcin Pilarczyk,Marcin Pilarczyk,Nicholas A. Clark,Nicholas A. Clark,Behrouz Shamsaei,Behrouz Shamsaei,Jarek Meller,Jarek Meller,Juozas Vasiliauskas,Juozas Vasiliauskas,John F. Reichard,John F. Reichard,Mario Medvedovic,Mario Medvedovic,Avi Ma'ayan,Ajay Pillai,Stephan C. Schürer,Stephan C. Schürer +51 more
TL;DR: TheLINCS Data Portal (LDP) is described, a unified web interface to access datasets generated by the LINCS DSGCs, and its underlying database, LINCS Data Registry (LDR).
Journal ArticleDOI
Electrophysiological studies of malaria parasite-infected erythrocytes: current status.
Henry M. Staines,Abdulnaser Alkhalil,Richard J.W. Allen,Hugo R. de Jonge,Elvira T. Derbyshire,Stéphane Egée,Hagai Ginsburg,David R.C. Hill,Stephan M. Huber,Kiaran Kirk,Florian Lang,Godfrey Lisk,Eugene K. Oteng,Ajay Pillai,Kempaiah Rayavara,Sherin J. Rouhani,Kevin J. Saliba,Crystal Shen,Tsione Solomon,Serge Thomas,Patrick Verloo,Sanjay A. Desai +21 more
TL;DR: The various models for altered transport are reviewed, together with the areas of consensus in the field and those that require a better understanding.
Journal ArticleDOI
Solute restriction reveals an essential role for clag3-associated channels in malaria parasite nutrient acquisition.
Ajay Pillai,Wang Nguitragool,Brian Lyko,Keithlee Dolinta,Michelle M. Butler,Son T. Nguyen,Norton P. Peet,Terry L. Bowlin,Sanjay A. Desai +8 more
TL;DR: Findings indicate that plasmodial surface anion channel functions in nutrient acquisition for intracellular parasites, and antimalarial drug development targeting PSAC should be pursued.