Anil K. Madugundu

TL;DR: A draft map of the human proteome is presented using high-resolution Fourier-transform mass spectrometry to discover a number of novel protein-coding regions, which includes translated pseudogenes, non-c coding RNAs and upstream open reading frames.

TL;DR: The sequences from deep RNA sequencing experiments by the Genotype-Tissue Expression (GTEx) project are assembled to create a new catalog of human genes and transcripts, called CHESS, revealing a heretofore unappreciated amount of transcriptional noise in human cells.

TL;DR: The signaling network of PfCDPK1 is delineated and light is shed on mechanisms via which it regulates invasion through phosphoproteomics and conditional knockdown, which establishes that this kinase is critical for the invasion of host erythrocytes.

TL;DR: The aim of this study is to identify the potential cerebrospinal fluid biomarkers for Alzheimer's disease and to evaluate these markers on independent CSF samples using parallel reaction monitoring (PRM) assays.

TL;DR: The utility of BioSITe is demonstrated when applied to proximity-dependent labeling methods, APEX and BioID, as well as biotin-based click chemistry strategies for identifying O-GlcNAc-modified sites and the use of isotopically labeled biotin for quantitative BioSITS experiments that simplify differential interactome analysis and obviate the need for metabolic labeling strategies such as SILAC.