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Anil K. Madugundu
Researcher at Manipal University
Publications - 70
Citations - 3447
Anil K. Madugundu is an academic researcher from Manipal University. The author has contributed to research in topics: Proteome & Proteomics. The author has an hindex of 17, co-authored 65 publications receiving 2700 citations. Previous affiliations of Anil K. Madugundu include National Institute of Mental Health and Neurosciences & Johns Hopkins University.
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Journal ArticleDOI
A draft map of the human proteome
Min-Sik Kim,Sneha M. Pinto,Derese Getnet,Raja Sekhar Nirujogi,Srikanth S. Manda,Raghothama Chaerkady,Anil K. Madugundu,Dhanashree S. Kelkar,Ruth Isserlin,Shobhit Jain,Joji Kurian Thomas,Babylakshmi Muthusamy,Pamela Leal-Rojas,Pamela Leal-Rojas,Praveen Kumar,Nandini A. Sahasrabuddhe,Lavanya Balakrishnan,Jayshree Advani,Bijesh George,Santosh Renuse,Lakshmi Dhevi N. Selvan,Arun H. Patil,Vishalakshi Nanjappa,Aneesha Radhakrishnan,Samarjeet Prasad,Tejaswini Subbannayya,Rajesh Raju,Manish Kumar,Sreelakshmi K. Sreenivasamurthy,Arivusudar Marimuthu,Gajanan Sathe,Sandip Chavan,Keshava K. Datta,Yashwanth Subbannayya,Apeksha Sahu,Soujanya D. Yelamanchi,Savita Jayaram,Pavithra Rajagopalan,Jyoti Sharma,Krishna R Murthy,Nazia Syed,Renu Goel,Aafaque Ahmad Khan,Sartaj Ahmad,Gourav Dey,Keshav Mudgal,Aditi Chatterjee,Tai-Chung Huang,Jun Zhong,Xinyan Wu,Patrick G. Shaw,Donald Freed,Muhammad Saddiq Zahari,Kanchan K Mukherjee,Subramanian Shankar,Anita Mahadevan,Henry H N Lam,Chris J. Mitchell,Susarla K. Shankar,Parthasarathy Satishchandra,John T. Schroeder,Ravi Sirdeshmukh,Anirban Maitra,Steven D. Leach,Charles G. Drake,Marc K. Halushka,T. S. Keshava Prasad,Ralph H. Hruban,Candace L. Kerr,Candace L. Kerr,Gary D. Bader,Christine A. Iacobuzio-Donahue,Harsha Gowda,Akhilesh Pandey +73 more
TL;DR: A draft map of the human proteome is presented using high-resolution Fourier-transform mass spectrometry to discover a number of novel protein-coding regions, which includes translated pseudogenes, non-c coding RNAs and upstream open reading frames.
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CHESS: a new human gene catalog curated from thousands of large-scale RNA sequencing experiments reveals extensive transcriptional noise
Mihaela Pertea,Mihaela Pertea,Alaina Shumate,Alaina Shumate,Geo Pertea,Ales Varabyou,Ales Varabyou,Florian P. Breitwieser,Yu Chi Chang,Anil K. Madugundu,Akhilesh Pandey,Akhilesh Pandey,Steven L. Salzberg +12 more
TL;DR: The sequences from deep RNA sequencing experiments by the Genotype-Tissue Expression (GTEx) project are assembled to create a new catalog of human genes and transcripts, called CHESS, revealing a heretofore unappreciated amount of transcriptional noise in human cells.
Journal ArticleDOI
PfCDPK1 mediated signaling in erythrocytic stages of Plasmodium falciparum
Sudhir Kumar,Manish Kumar,Roseleen Ekka,Jeffrey D. Dvorin,Jeffrey D. Dvorin,Aditya S. Paul,Anil K. Madugundu,Tim W. Gilberger,Harsha Gowda,Manoj T. Duraisingh,T. S. Keshava Prasad,T. S. Keshava Prasad,Pushkar Sharma +12 more
TL;DR: The signaling network of PfCDPK1 is delineated and light is shed on mechanisms via which it regulates invasion through phosphoproteomics and conditional knockdown, which establishes that this kinase is critical for the invasion of host erythrocytes.
Journal ArticleDOI
Quantitative Proteomic Profiling of Cerebrospinal Fluid to Identify Candidate Biomarkers for Alzheimer's Disease.
Gajanan Sathe,Chan Hyun Na,Santosh Renuse,Anil K. Madugundu,Marilyn S. Albert,Abhay Moghekar,Akhilesh Pandey +6 more
TL;DR: The aim of this study is to identify the potential cerebrospinal fluid biomarkers for Alzheimer's disease and to evaluate these markers on independent CSF samples using parallel reaction monitoring (PRM) assays.
Journal ArticleDOI
BioSITe: A Method for Direct Detection and Quantitation of Site-Specific Biotinylation.
Dae In Kim,Jevon Cutler,Chan Hyun Na,Sina Reckel,Santosh Renuse,Anil K. Madugundu,Raiha Tahir,Hana L. Goldschmidt,Karen L. Reddy,Richard L. Huganir,Xinyan Wu,Natasha E. Zachara,Oliver Hantschel,Akhilesh Pandey +13 more
TL;DR: The utility of BioSITe is demonstrated when applied to proximity-dependent labeling methods, APEX and BioID, as well as biotin-based click chemistry strategies for identifying O-GlcNAc-modified sites and the use of isotopically labeled biotin for quantitative BioSITS experiments that simplify differential interactome analysis and obviate the need for metabolic labeling strategies such as SILAC.