Charles Antzelevitch

TL;DR: A draft standard for recording, annotating, and reporting experimental data, called Minimum Information about a Cardiac Electrophysiology Experiment (MICEE) is presented, with the ultimate goal of developing a useful tool for cardiac electrophysiologists which facilitates and improves dissemination of the minimum information necessary for reproduction of cardiac electrophic research.

TL;DR: The presence of a prominent notch in the action potential of ventricular epicardium but not endocardium gives rise to a transmural voltage gradient during ventricular activation that manifests as a late delta wave following the QRS or what is commonly referred to as a J wave 1 or Osborn wave.

TL;DR: 2 distinctly different mechanisms involving 1) loss of the epicardial action potential dome and 2) markedly delayed transmural conduction underlie the apparent ST-segment elevation encountered during acute ischemia are probed.

TL;DR: The Brugada syndrome is an arrhythmic syndrome characterized by a right bundle branch block pattern and ST segment elevation in the right precordial leads of the electrocardiogram in conjunction with a high incidence of sudden death secondary to ventricular tachyarrhythmias.

TL;DR: Three new SCN 5A mutations in Brugada syndrome patients are all located within domain I of SCN5A, a region not previously considered important in the development of ventricular arrhythmias.