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Daniel R. Brison

Researcher at University of Manchester

Publications -  125
Citations -  8398

Daniel R. Brison is an academic researcher from University of Manchester. The author has contributed to research in topics: Embryo & Embryonic stem cell. The author has an hindex of 38, co-authored 112 publications receiving 7432 citations. Previous affiliations of Daniel R. Brison include St Mary's Hospital & University of Pennsylvania.

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Metabolomics: Current technologies and future trends

TL;DR: In this article, an overview of metabolomics and its complementary role with transcriptomics and proteomics, and within system biology is presented, highlighting how metabolome analyses are conducted and how the highly complex data that are generated are analyzed.
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Screening ethnically diverse human embryonic stem cells identifies a chromosome 20 minimal amplicon conferring growth advantage

Katherine Amps, +124 more
- 27 Nov 2011 - 
TL;DR: Of these genes, BCL2L1 is a strong candidate for driving culture adaptation of ES cells, and single-nucleotide polymorphism analysis revealed that they included representatives of most major ethnic groups.
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The spectrum of DNA damage in human sperm assessed by single cell gel electrophoresis (Comet assay) and its relationship to fertilization and embryo development.

TL;DR: High loads of DNA damage measured by the Comet assay were predictive of failure of embryo development after ICSI, and it is likely that sperm with DNA damage contributed to successful fertilization and in-vitro development.
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Apoptosis during mouse blastocyst formation: evidence for a role for survival factors including transforming growth factor alpha.

TL;DR: Results of these experiments suggest that endogenously produced growth factors may function as cell survival factors during preimplantation development.