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Martin R. Farlow

Researcher at Indiana University

Publications -  50
Citations -  6873

Martin R. Farlow is an academic researcher from Indiana University. The author has contributed to research in topics: Alzheimer's disease & Dementia. The author has an hindex of 28, co-authored 50 publications receiving 5881 citations. Previous affiliations of Martin R. Farlow include Indiana University – Purdue University Indianapolis & University of Alabama at Birmingham.

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Journal ArticleDOI

Common variants at MS4A4/MS4A6E, CD2AP, CD33 and EPHA1 are associated with late-onset Alzheimer's disease.

Adam C. Naj, +156 more
- 01 May 2011 - 
TL;DR: The Alzheimer Disease Genetics Consortium performed a genome-wide association study of late-onset Alzheimer disease using a three-stage design consisting of a discovery stage (stage 1), two replication stages (stages 2 and 3), and both joint analysis and meta-analysis approaches were used.
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Molecular basis of phenotypic variability in sporadic Creutzfeldt-Jakob disease.

Piero Parchi, +11 more
- 01 Jun 1996 - 
TL;DR: The data indicate that the sporadic form of Creutzfeldt‐Jakob disease comprises a limited number of variants, and the methionine/valine polymorphism at codon 129 of the prion protein gene and two types of protease‐resistant prion proteins are the major determinants of these variants.
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Rare coding variants in PLCG2, ABI3, and TREM2 implicate microglial-mediated innate immunity in Alzheimer's disease

Rebecca Sims, +487 more
- 01 Sep 2017 - 
TL;DR: Three new genome-wide significant nonsynonymous variants associated with Alzheimer's disease are observed, providing additional evidence that the microglia-mediated innate immune response contributes directly to the development of Alzheimer's Disease.
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Cerebrospinal Fluid Tau and β-Amyloid: How Well Do These Biomarkers Reflect Autopsy-Confirmed Dementia Diagnoses?

Christopher M. Clark, +18 more
- 01 Dec 2003 - 
TL;DR: Elevated CSF tau levels are associated with AD pathology and can help discriminate AD from other dementing disorders, however, some patients with AD have a level less than the mean +/- 2 SDs of the cognitively normal cohort.
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A soluble phosphorylated tau signature links tau, amyloid and the evolution of stages of dominantly inherited Alzheimer's disease.

Nicolas R. Barthélemy, +42 more
- 11 Mar 2020 - 
TL;DR: A pattern of tau staging is identified where site-specific phosphorylation changes occur at different periods of disease progression and follow distinct trajectories over time, providing insights into the pathways linking tau, amyloid-β and neurodegeneration in dominantly inherited Alzheimer's disease.