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Derrick W. Crook

Researcher at University of Oxford

Publications -  510
Citations -  38699

Derrick W. Crook is an academic researcher from University of Oxford. The author has contributed to research in topics: Population & Medicine. The author has an hindex of 92, co-authored 474 publications receiving 29885 citations. Previous affiliations of Derrick W. Crook include Oxford Brookes University & The Chinese University of Hong Kong.

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Genomic islands: tools of bacterial horizontal gene transfer and evolution.

TL;DR: Genomic islands play a crucial role in the evolution of a broad spectrum of bacteria as they are involved in the dissemination of variable genes, including antibiotic resistance and virulence genes leading to generation of hospital ‘superbugs’, as well as catabolic genes lead to formation of new metabolic pathways.
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SARS-CoV-2 Omicron-B.1.1.529 leads to widespread escape from neutralizing antibody responses

TL;DR: In this article , a new SARS-CoV-2 viral isolate Omicron-B.1.529 was announced, containing far more mutations in Spike (S) than previously reported variants, leading to a large number of mutations in the ACE2 binding site and rebalances receptor affinity to that of earlier pandemic viruses.
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Prospective evaluation of criteria for microbiological diagnosis of prosthetic-joint infection at revision arthroplasty. The OSIRIS Collaborative Study Group.

TL;DR: It is recommended that five or six specimens be sent, that the cutoff for a definite diagnosis of infection be three or more operative specimens that yield an indistinguishable organism, and that because of its low level of sensitivity, Gram staining should be abandoned as a diagnostic tool at elective revision arthroplasty.