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Istvan Vajtai
Researcher at University of Bern
Publications - 69
Citations - 2021
Istvan Vajtai is an academic researcher from University of Bern. The author has contributed to research in topics: Oligodendroglioma & Ependymoma. The author has an hindex of 21, co-authored 69 publications receiving 1735 citations.
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Journal ArticleDOI
New Brain Tumor Entities Emerge from Molecular Classification of CNS-PNETs
Dominik Sturm,Dominik Sturm,Brent A. Orr,Umut H. Toprak,Volker Hovestadt,David T.W. Jones,David Capper,David Capper,Martin Sill,Ivo Buchhalter,Paul A. Northcott,Irina Leis,Marina Ryzhova,Christian Koelsche,Christian Koelsche,Elke Pfaff,Elke Pfaff,Sariah Allen,Gnanaprakash Balasubramanian,Barbara C. Worst,Barbara C. Worst,Kristian W. Pajtler,Sebastian Brabetz,Pascal Johann,Pascal Johann,Felix Sahm,Felix Sahm,Jüri Reimand,Jüri Reimand,Alan Mackay,Diana Carvalho,Marc Remke,Joanna J. Phillips,Arie Perry,Cynthia Cowdrey,Rachid Drissi,Maryam Fouladi,Felice Giangaspero,Maria Łastowska,Wiesława Grajkowska,Wolfram Scheurlen,Torsten Pietsch,Christian Hagel,Johannes Gojo,Daniela Lötsch,Walter Berger,Irene Slavc,Christine Haberler,Anne Jouvet,Stefan Holm,Silvia Hofer,Marco Prinz,Catherine Keohane,Iris Fried,Christian Mawrin,David Scheie,Bret C. Mobley,Matthew Schniederjan,Mariarita Santi,Anna Maria Buccoliero,Sonika Dahiya,Christof M. Kramm,André O. von Bueren,Katja von Hoff,Stefan Rutkowski,Christel Herold-Mende,Michael C. Frühwald,Till Milde,Till Milde,Martin Hasselblatt,Pieter Wesseling,Pieter Wesseling,Jochen Rößler,Ulrich Schüller,Martin Ebinger,Jens Schittenhelm,Stephan Frank,Rainer Grobholz,Istvan Vajtai,Volkmar Hans,Reinhard Schneppenheim,Karel Zitterbart,V. Peter Collins,Eleonora Aronica,Pascale Varlet,Stéphanie Puget,Christelle Dufour,Jacques Grill,Dominique Figarella-Branger,Marietta Wolter,Martin U. Schuhmann,Tarek Shalaby,Michael A. Grotzer,Timothy E. Van Meter,Camelia M. Monoranu,Jörg Felsberg,Guido Reifenberger,Matija Snuderl,Lynn Ann Forrester,Jan Koster,Rogier Versteeg,Richard Volckmann,Peter van Sluis,Stephan Wolf,Tom Mikkelsen,Amar Gajjar,Kenneth Aldape,Andrew S. Moore,Michael D. Taylor,Chris Jones,Nada Jabado,Matthias A. Karajannis,Roland Eils,Matthias Schlesner,Peter Lichter,Andreas von Deimling,Andreas von Deimling,Stefan M. Pfister,Stefan M. Pfister,David W. Ellison,Andrey Korshunov,Andrey Korshunov,Marcel Kool +122 more
TL;DR: It is demonstrated that a significant proportion of institutionally diagnosed CNS-PNETs display molecular profiles indistinguishable from those of various other well-defined CNS tumor entities, facilitating diagnosis and appropriate therapy for patients with these tumors.
Journal ArticleDOI
IDH/MGMT-driven molecular classification of low-grade glioma is a strong predictor for long-term survival
Severina Leu,Stefanie von Felten,Stephan Frank,Erik Vassella,Istvan Vajtai,Elisabeth Taylor,Marianne Schulz,Gregor Hutter,Jürgen Hench,Philippe Schucht,Jean-Louis Boulay,Luigi Mariani +11 more
TL;DR: By integrating networks of activated molecular glioma pathways, the model based on genotype better predicts prognosis than histology and, therefore, provides a more reliable tool for standardizing future treatment strategies.
Journal ArticleDOI
Loss of Heterozygosity 1p36 and 19q13 Is a Prognostic Factor for Overall Survival in Patients With Diffuse WHO Grade 2 Gliomas Treated Without Chemotherapy
Luigi Mariani,Gianluca Deiana,Erik Vassella,Ali-Reza Fathi,Christine Murtin,Marlene Arnold,Istvan Vajtai,Joachim Weis,Peter Siegenthaler,Martina Schobesberger,Michael Reinert +10 more
TL;DR: The presence of LOH on either 1p36 or 19q13, and in particular codeletion of both loci, is a strong, nontreatment-related, prognostic factor for overall survival in patients with diffusely infiltrating WHO grade 2 gliomas treated without chemotherapy.
Journal ArticleDOI
Metabolic pathway and distribution of superparamagnetic iron oxide nanoparticles: in vivo study.
Eva K Schlachter,Hans Ruedi Widmer,Amade Bregy,Tarja Lönnfors-Weitzel,Istvan Vajtai,Nadia Corazza,Vianney J.P. Bernau,Thilo Weitzel,Pasquale Mordasini,Johannes Slotboom,Gudrun Herrmann,Serge Bogni,Heinrich Hofmann,Martin Frenz,Michael Reinert +14 more
TL;DR: Systemic bioavailability may play a role in specific SPION implant toxicity and therefore the local degradation process is a further aspect to be assessed in future studies.
Journal ArticleDOI
Pituitary surgery for small prolactinomas as an alternative to treatment with dopamine agonists
TL;DR: Patients with small prolactinomas can safely consider pituitary surgery in a specialized centre with good chance of long-term remission as an alternative to long- term DA therapy.