L
Lisa Pennells
Researcher at University of Cambridge
Publications - 43
Citations - 8945
Lisa Pennells is an academic researcher from University of Cambridge. The author has contributed to research in topics: Population & Medicine. The author has an hindex of 19, co-authored 30 publications receiving 6437 citations. Previous affiliations of Lisa Pennells include Istituto Superiore di Sanità.
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Journal ArticleDOI
Diabetes mellitus, fasting blood glucose concentration, and risk of vascular disease: a collaborative meta-analysis of 102 prospective studies
Nadeem Sarwar,Pei Gao,Seshasai Srk.,Reeta Gobin,Stephen Kaptoge,E Di Angelantonio,Erik Ingelsson,Debbie A Lawlor,Elizabeth Selvin,Meir J. Stampfer,Stehouwer Cda.,Sarah Lewington,Lisa Pennells,Alexander M. W. Cargill Thompson,Naveed Sattar,Ian R. White,Kausik K. Ray,John Danesh +17 more
TL;DR: A meta-analysis of individual records of diabetes, fasting blood glucose concentration, and other risk factors in people without initial vascular disease from studies in the Emerging Risk Factors Collaboration found diabetes confers about a two-fold excess risk for a wide range of vascular diseases, independently from other conventional risk factors.
Journal ArticleDOI
C-Reactive Protein, Fibrinogen, and Cardiovascular Disease Prediction
Stephen Kaptoge,Emanuele Di Angelantonio,Lisa Pennells,Angela M. Wood,Ian R. White,Pei Gao,Matthew G. Walker,Alexander M. W. Cargill Thompson,Nadeem Sarwar,Muriel J. Caslake,Adam S. Butterworth,Philippe Amouyel,Gerd Assmann,Stephan J. L. Bakker,Elizabeth L M Barr,Elizabeth Barrett-Connor,Emelia J. Benjamin,Cecilia Björkelund,Hermann Brenner,Eric J. Brunner,Robert Clarke,Jackie A. Cooper,Peter Cremer,Mary Cushman,Gilles R. Dagenais,Ralph B. D'Agostino,Rachel Dankner,George Davey-Smith,Dorly J. H. Deeg,Jacqueline M. Dekker,Gunnar Engström,Aaron R. Folsom,F. Gerry R. Fowkes,John Gallacher,J. Michael Gaziano,Simona Giampaoli,Richard F. Gillum,Albert Hofman,Barbara V. Howard,Erik Ingelsson,Hiroyasu Iso,Torben Jørgensen,Stefan Kiechl,Akihiko Kitamura,Yutaka Kiyohara,Wolfgang Koenig,Daan Kromhout,Lewis H. Kuller,Debbie A Lawlor,Tom W. Meade,Aulikki Nissinen,Børge G. Nordestgaard,Altan Onat,Demosthenes B. Panagiotakos,Bruce M. Psaty,Beatriz L. Rodriguez,Annika Rosengren,Veikko Salomaa,Jussi Kauhanen,Jukka T. Salonen,Jonathan A. Shaffer,Steven Shea,Ian Ford,Coen D.A. Stehouwer,Timo E. Strandberg,Robert W. Tipping,Alberto Tosetto,Sylvia Wassertheil-Smoller,Patrik Wennberg,Rudi G. J. Westendorp,Peter H. Whincup,Lars Wilhelmsen,Mark Woodward,Gordon D.O. Lowe,Nicholas J. Wareham,Kay-Tee Khaw,Naveed Sattar,Chris J. Packard,Vilmundur Gudnason,Paul M. Ridker,Mark B. Pepys,Simon G. Thompson,John Danesh +82 more
TL;DR: It is estimated that under current treatment guidelines, assessment of the CRP or fibrinogen level in people at intermediate risk for a cardiovascular event could help prevent one additional event over a period of 10 years for every 400 to 500 people screened.
Journal ArticleDOI
Separate and combined associations of body-mass index and abdominal adiposity with cardiovascular disease: collaborative analysis of 58 prospective studies
David Wormser,Stephen Kaptoge,E Di Angelantonio,Angela M. Wood,Lisa Pennells,Alexander M. W. Cargill Thompson,Nadeem Sarwar,Jorge R. Kizer,Debbie A Lawlor,Børge G. Nordestgaard,Paul M. Ridker,V. Salomaa,June Stevens,Mark Woodward,Naveed Sattar,Rory Collins,Simon G. Thompson,Gary Whitlock,John Danesh +18 more
TL;DR: BMI, waist circumference, and waist-to-hip ratio, whether assessed singly or in combination, do not importantly improve cardiovascular disease risk prediction in people in developed countries when additional information is available for systolic blood pressure, history of diabetes, and lipids.
Journal ArticleDOI
Association of Cardiometabolic Multimorbidity With Mortality
Emanuele Di Angelantonio,Stephen Kaptoge,David Wormser,Peter Willeit,Adam S. Butterworth,Narinder Bansal,Linda M. O’Keeffe,Pei Gao,Angela M. Wood,Stephen Burgess,Daniel F. Freitag,Lisa Pennells,Sanne A.E. Peters,Carole L. Hart,Lise Lund Håheim,Richard F. Gillum,Børge G. Nordestgaard,Bruce M. Psaty,Bu B. Yeap,Matthew Knuiman,Paul J. Nietert,Jussi Kauhanen,Jukka T. Salonen,Lewis H. Kuller,Leon A. Simons,Yvonne T. van der Schouw,Elizabeth Barrett-Connor,Randi Selmer,Carlos J. Crespo,Beatriz L. Rodriguez,W. M. Monique Verschuren,Veikko Salomaa,Kurt Svärdsudd,Pim van der Harst,Cecilia Björkelund,Lars Wilhelmsen,Robert B. Wallace,Hermann Brenner,Philippe Amouyel,Elizabeth L M Barr,Hiroyasu Iso,Altan Onat,Maurizio Trevisan,Ralph B. D'Agostino,Cyrus Cooper,Cyrus Cooper,Maryam Kavousi,Lennart Welin,Ronan Roussel,Ronan Roussel,Frank B. Hu,Shinichi Sato,Karina W. Davidson,Barbara V. Howard,Maarten J.G. Leening,Annika Rosengren,Marcus Dörr,Dorly J. H. Deeg,Stefan Kiechl,Coen D.A. Stehouwer,Aulikki Nissinen,Simona Giampaoli,Chiara Donfrancesco,Daan Kromhout,Jackie F. Price,Annette Peters,Tom W. Meade,Edoardo Casiglia,Debbie A Lawlor,John Gallacher,Dorothea Nagel,Oscar H. Franco,Gerd Assmann,Gilles R. Dagenais,J. Wouter Jukema,Johan Sundström,Mark Woodward,Eric J. Brunner,Kay-Tee Khaw,Nicholas J. Wareham,Eric A. Whitsel,Inger Njølstad,Bo Hedblad,Sylvia Wassertheil-Smoller,Gunnar Engström,Wayne D. Rosamond,Elizabeth Selvin,Naveed Sattar,Simon G. Thompson,John Danesh +89 more
TL;DR: Because any combination of these conditions was associated with multiplicative mortality risk, life expectancy was substantially lower in people with multimorbidity.
Journal ArticleDOI
World Health Organization cardiovascular disease risk charts: revised models to estimate risk in 21 global regions
Stephen Kaptoge,Lisa Pennells,Dirk De Bacquer,Marie Therese Cooney,Maryam Kavousi,Gretchen A Stevens,Leanne M. Riley,Stefan Savin,Taskeen Khan,Servet Altay,Philippe Amouyel,Gerd Assmann,Steven Bell,Yoav Ben-Shlomo,Lisa F. Berkman,Joline W.J. Beulens,Cecilia Björkelund,Michael J. Blaha,Dan G. Blazer,Thomas Bolton,Ruth Bonita Beaglehole,Hermann Brenner,Eric J. Brunner,Edoardo Casiglia,Parinya Chamnan,Yeun Hyang Choi,Rajiv Chowdry,Sean Coady,Carlos J. Crespo,Mary Cushman,Gilles R. Dagenais,Ralph B. D'Agostino,Makoto Daimon,Karina W. Davidson,Gunnar Engström,Ian Ford,John Gallacher,Ron T. Gansevoort,Thomas A. Gaziano,Simona Giampaoli,Greg Grandits,Sameline Grimsgaard,Diederick E. Grobbee,Vilmundur Gudnason,Qi Guo,Hanna Tolonen,Steve E. Humphries,Hiroyasu Iso,J. Wouter Jukema,Jussi Kauhanen,Andre Pascal Kengne,Davood Khalili,Wolfgang Koenig,Daan Kromhout,Harlan M. Krumholz,Tai Hing Lam,Gail A. Laughlin,Alejandro Marín Ibañez,Tom W. Meade,Karel G.M. Moons,Paul J. Nietert,Toshiharu Ninomiya,Børge G. Nordestgaard,Christopher J. O'Donnell,Luigi Palmieri,Anushka Patel,Pablo Perel,Jackie F. Price,Rui Providência,Paul M. Ridker,Beatriz L. Rodriguez,Annika Rosengren,Ronan Roussel,Masaru Sakurai,Veikko Salomaa,Shinichi Sato,Ben Schöttker,Nawar Shara,Jonathan E. Shaw,Hee Choon Shin,Leon A. Simons,Eleni Sofianopoulou,Johan Sundström,Henry Völzke,Robert B. Wallace,Nicholas J. Wareham,Peter Willeit,Darien Wood,Angela M. Wood,Dong Zhao,Mark Woodward,Goodarz Danaei,Gregory A. Roth,Shanthi Mendis,Oyere K Onuma,Cherian Varghese,Majid Ezzati,Ian D. Graham,Rod Jackson,John Danesh,Emanuele Di Angelantonio +100 more
TL;DR: The derivation, validation, and illustration of the revised WHO cardiovascular disease risk prediction charts that have been adapted to the circumstances of 21 global regions are reported.