J
Jean-Louis Laplanche
Researcher at University of Paris
Publications - 193
Citations - 8985
Jean-Louis Laplanche is an academic researcher from University of Paris. The author has contributed to research in topics: PRNP & Gene. The author has an hindex of 48, co-authored 183 publications receiving 8218 citations. Previous affiliations of Jean-Louis Laplanche include Paris Diderot University & French Institute of Health and Medical Research.
Papers
More filters
Journal ArticleDOI
Signal transduction through prion protein.
Sophie Mouillet-Richard,Myriam Ermonval,C Chebassier,Jean-Louis Laplanche,Sylvain Lehmann,Jean-Marie Launay,Odile Kellermann +6 more
TL;DR: The murine 1C11 neuronal differentiation model was used to search for PrPc-dependent signal transduction through antibody-mediated cross-linking and a caveolin-1-dependent coupling of PrPC to the tyrosine kinase Fyn was observed.
Journal ArticleDOI
Analysis of EEG and CSF 14-3-3 proteins as aids to the diagnosis of Creutzfeldt-Jakob disease.
Inga Zerr,Maurizio Pocchiari,Steven J. Collins,J.-P. Brandel,J de Pedro Cuesta,Richard Knight,H. Bernheimer,Franco Cardone,N. Delasnerie-Laupretre,N. Cuadrado Corrales,Anna Ladogana,Monika Bodemer,Ashley Fletcher,T. Awan,A. Ruiz Bremón,Herbert Budka,Jean-Louis Laplanche,Robert G. Will,Sigrid Poser +18 more
TL;DR: In this paper, a comparison of clinical and neuropathologic diagnoses and evaluation of the sensitivity and specificity of EEG and 14-3-3 CSF immunoassay were conducted.
Journal ArticleDOI
Quantifying prion disease penetrance using large population control cohorts
Eric Vallabh Minikel,Eric Vallabh Minikel,Sonia M Vallabh,Sonia M Vallabh,Monkol Lek,Monkol Lek,Karol Estrada,Karol Estrada,Kaitlin E. Samocha,Kaitlin E. Samocha,J. Fah Sathirapongsasuti,Cory Y. McLean,Joyce Y. Tung,Linda P.C. Yu,Pierluigi Gambetti,Janis Blevins,Shulin Na Zhang,Yvonne Cohen,Wei Chen,Masahito Yamada,Tsuyoshi Hamaguchi,Nobuo Sanjo,Hidehiro Mizusawa,Yosikazu Nakamura,Tetsuyuki Kitamoto,Steven J. Collins,Alison Boyd,Robert G. Will,Richard Knight,Claudia Ponto,Inga Zerr,Theo F. J. Kraus,Sabina Eigenbrod,Armin Giese,Miguel Calero,Jesús de Pedro-Cuesta,Stéphane Haïk,Jean-Louis Laplanche,Elodie Bouaziz-Amar,Jean Philippe Brandel,Sabina Capellari,Piero Parchi,Anna Poleggi,Anna Ladogana,Anne H. O’Donnell-Luria,Anne H. O’Donnell-Luria,Konrad J. Karczewski,Konrad J. Karczewski,Jamie L. Marshall,Jamie L. Marshall,Michael Boehnke,Markku Laakso,Karen L. Mohlke,Anna K. Kähler,Kimberly Chambert,Steven A. McCarroll,Patrick F. Sullivan,Patrick F. Sullivan,Christina M. Hultman,Shaun Purcell,Pamela Sklar,Sven J. van der Lee,Annemieke J. M. Rozemuller,Casper Jansen,Albert Hofman,Robert Kraaij,Jeroen van Rooij,M. Arfan Ikram,André G. Uitterlinden,Cornelia M. van Duijn,Mark J. Daly,Mark J. Daly,Daniel G. MacArthur,Daniel G. MacArthur +73 more
TL;DR: It is shown that missense variants in PRNP previously reported to be pathogenic are at least 30 times more common in the population than expected on the basis of genetic prion disease prevalence, a finding that supports the safety of therapeutic suppression of prion protein expression.
Journal ArticleDOI
CSF biomarker variability in the Alzheimer's Association quality control program
Niklas Mattsson,Niklas Mattsson,Ulf Andreasson,Staffan Persson,Maria C. Carrillo,Steven J. Collins,Sonia Chalbot,Neal Cutler,Diane Dufour-Rainfray,Anne M. Fagan,Niels H. H. Heegaard,Ging-Yuek Robin Hsiung,Bradley T. Hyman,Khalid Iqbal,D. Richard Lachno,Alberto Lleó,Piotr Lewczuk,José Luis Molinuevo,Piero Parchi,Axel Regeniter,Robert A. Rissman,Hanna Rosenmann,Giuseppe Sancesario,Johannes Schröder,Leslie M. Shaw,Charlotte E. Teunissen,John Q. Trojanowski,Hugo Vanderstichele,Manu Vandijck,Marcel M. Verbeek,Henrik Zetterberg,Henrik Zetterberg,Kaj Blennow,Stephan A. Käser,Aladro José A. Rojo,Marilyn S. Albert,Daniel Alcolea,Anna Antonell,Hiroyuki Arai,Silvana Archetti,Eva Arkblad,Inês Baldeiras,Ales Bartos,Dev Batish,Aurélie Bedel,Daniele Bentue-Ferrer,Flora Berisha,Sergio Bernardini,Marinus A. Blankenstein,Olivier Bousiges,Michael C. Camuso,Maria Berrocal Carrillo,Tiziana Casoli,Sebastiano Cavallaro,Odete A. da Cruz e Silva,Isabelle Cuvelier,Odile Delaroche,Roy B. Dyer,Sebastiaan Engelborghs,Anne Fogli,Orestes Vicente Forlenza,Nick C. Fox,Giovanni B. Frisoni,Daniela Galimberti,Elisabetta Galloni,Silvana Gritti,Karen H. Gylys,Harald Hampel,Sabine Haustein,Theresa Heath,Michael T. Heneka,Sanna-Kaisa Herukka,David M. Holtzman,Christian Humpel,Takeshi Iwatsubo,Claude Jardel,Mathias Jucker,Elisabeth Kapaki,Daniel Kidd,Péter Klivényi,Ryozo Kuwano,Foudil Lamari,Jean-Louis Laplanche,Jordan Laser,Sylvian Lehmann,Qiao-Xin Li,Walter Maetzler,Catherine Malaplate-Armand,Ralph Martin,Robert Martone,Colin L. Masters,Marc Mercken,Jose Luis Molinuevo,T. J. Montine,William Nowatzke,Markus Otto,Xavier Parent,Lucilla Parnetti,Ronald C. Petersen,Koen Poesen,Isabelle Quadrio,Muriel Quillard,Vara Luis Rello,Zdenek Rohan,Christin Sisowath,Anders Skinningsrud,Holly Soares,Hilkka Soininen,Knudsen Cindy Søndersø,Annette Spreer,Silvia Suardi,C.E. Teunissen,Robert M. Umek,Bianca Van Broeck,Rik Vandenberghe,László Vécsei,M.M. Verbeek,Igor Vostiar,Manfred Windisch +118 more
TL;DR: The cerebrospinal fluid biomarkers amyloid beta 1–42, total tau, and phosphorylated tau are used increasingly for Alzheimer's disease research and patient management, but there are large variations in biomarker measurements among and within laboratories.
Journal ArticleDOI
Distinct molecular phenotypes in bovine prion diseases
TL;DR: The existence of an atypical molecular phenotype among cattle diagnosed with BSE in France suggests either some phenotypic modifications of PrPres following infection by the BSE agent or the existence of alternative origins of such diseases in cattle.