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Sven J. van der Lee

Researcher at VU University Amsterdam

Publications -  101
Citations -  12071

Sven J. van der Lee is an academic researcher from VU University Amsterdam. The author has contributed to research in topics: Genome-wide association study & Population. The author has an hindex of 38, co-authored 101 publications receiving 9456 citations. Previous affiliations of Sven J. van der Lee include Harvard University & Erasmus University Rotterdam.

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Analysis of shared heritability in common disorders of the brain

Verneri Anttila, +720 more
- 22 Jun 2018 - 
TL;DR: It is demonstrated that, in the general population, the personality trait neuroticism is significantly correlated with almost every psychiatric disorder and migraine, and it is shown that both psychiatric and neurological disorders have robust correlations with cognitive and personality measures.
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Genome-wide association study identifies 74 loci associated with educational attainment

Aysu Okbay, +296 more
- 26 May 2016 - 
TL;DR: In this article, the results of a genome-wide association study (GWAS) for educational attainment were reported, showing that single-nucleotide polymorphisms associated with educational attainment disproportionately occur in genomic regions regulating gene expression in the fetal brain.

Genome-wide association study identifies 74 loci associated with educational attainment

Aysu Okbay, +254 more
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Genetic variants associated with subjective well-being, depressive symptoms, and neuroticism identified through genome-wide analyses

Aysu Okbay, +216 more
- 01 Jun 2016 - 
TL;DR: In this paper, the authors conducted genome-wide association studies of three phenotypes: subjective well-being (n = 298,420), depressive symptoms (n= 161,460), and neuroticism(n = 170,911).
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Rare coding variants in PLCG2, ABI3, and TREM2 implicate microglial-mediated innate immunity in Alzheimer's disease

Rebecca Sims, +487 more
- 01 Sep 2017 - 
TL;DR: Three new genome-wide significant nonsynonymous variants associated with Alzheimer's disease are observed, providing additional evidence that the microglia-mediated innate immune response contributes directly to the development of Alzheimer's Disease.