M
Marita Troye-Blomberg
Researcher at Stockholm University
Publications - 239
Citations - 10277
Marita Troye-Blomberg is an academic researcher from Stockholm University. The author has contributed to research in topics: Plasmodium falciparum & Malaria. The author has an hindex of 58, co-authored 239 publications receiving 9760 citations.
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Journal ArticleDOI
Genome-wide and fine-resolution association analysis of malaria in West Africa
Muminatou Jallow,Yik Ying Teo,Yik Ying Teo,Kerrin S. Small,Kerrin S. Small,Kirk A. Rockett,Kirk A. Rockett,Panos Deloukas,Taane G. Clark,Taane G. Clark,Katja Kivinen,Kalifa Bojang,David J. Conway,Margaret Pinder,Giorgio Sirugo,Fatou Sisay-Joof,Stanley Usen,Sarah Auburn,Sarah Auburn,Suzannah Bumpstead,Susana Campino,Susana Campino,Alison J. Coffey,Andrew Dunham,Andrew E. Fry,Angela Green,Rhian Gwilliam,Sarah E. Hunt,Michael Inouye,Anna E. Jeffreys,Alieu Mendy,Aarno Palotie,Simon C. Potter,Jiannis Ragoussis,Jane Rogers,Kate Rowlands,Elilan Somaskantharajah,Pamela Whittaker,Claire Widden,Peter Donnelly,Bryan Howie,Jonathan Marchini,Andrew P. Morris,Miguel A. Sanjoaquin,Miguel A. Sanjoaquin,Eric A. Achidi,Tsiri Agbenyega,Angela Allen,Angela Allen,Olukemi K. Amodu,Patrick H. Corran,Abdoulaye A. Djimde,Amagana Dolo,Ogobara K. Doumbo,Chris Drakeley,Sarah J. Dunstan,Jennifer Evans,Jennifer Evans,Jeremy Farrar,Deepika Fernando,Tran Tinh Hien,Rolf D. Horstmann,Muntaser E. Ibrahim,Nadira D. Karunaweera,Gilbert Kokwaro,Kwadwo A. Koram,Martha M. Lemnge,Julie Makani,Kevin Marsh,Pascal Michon,David Modiano,Malcolm E. Molyneux,Ivo Mueller,Michael Parker,Norbert Peshu,Christopher V. Plowe,Odile Puijalon,John C. Reeder,Hugh Reyburn,Eleanor M. Riley,Anavaj Sakuntabhai,Pratap Singhasivanon,Sodiomon B. Sirima,Adama Tall,Terrie E. Taylor,Mahamadou A. Thera,Marita Troye-Blomberg,Thomas N. Williams,Michael T. Wilson,Dominic P. Kwiatkowski,Dominic P. Kwiatkowski +90 more
TL;DR: These findings provide proof of principle that fine-resolution multipoint imputation, based on population-specific sequencing data, can substantially boost authentic GWA signals and enable fine mapping of causal variants in African populations.
Journal Article
Th1/Th2 profiles in tuberculosis, based on the proliferation and cytokine response of blood lymphocytes to mycobacterial antigens.
H M Surcel,Marita Troye-Blomberg,Staffan Paulie,G Andersson,C Moreno,Geoffrey Pasvol,J Ivanyi +6 more
TL;DR: It is concluded that the demonstrated Th2 type of profile in response to two prominent mycobacterial antigens may play a role in the mechanisms of defective host resistance in tuberculosis.
Journal ArticleDOI
TLR4 polymorphisms, infectious diseases, and evolutionary pressure during migration of modern humans
Bart Ferwerda,Matthew B. B. McCall,Santos Alonso,Evangelos J. Giamarellos-Bourboulis,Maria Mouktaroudi,Neskuts Izagirre,Din Syafruddin,Gibson S. Kibiki,Tudor Cristea,Anneke Hijmans,Lutz Hamann,Shoshana Israel,Gehad ElGhazali,Marita Troye-Blomberg,Oliver Kumpf,B. Maiga,Amagana Dolo,Ogobara K. Doumbo,Cornelus C. Hermsen,Anton F. H. Stalenhoef,Reinout van Crevel,Han G. Brunner,Djin-Ye Oh,Ralf R. Schumann,Concepción de la Rúa,Robert W. Sauerwein,Bart Jan Kullberg,André J. A. M. van der Ven,Jos W. M. van der Meer,Mihai G. Netea +29 more
TL;DR: Polymorphisms in TLR4 exemplify how the interaction between the authors' innate immune system and the infectious pressures in particular environments may have shaped the genetic variations and function of their immune system during the out-of-Africa migration of modern humans.
Journal ArticleDOI
Granulysin-Dependent Killing of Intracellular and Extracellular Mycobacterium tuberculosis by Vγ9/Vδ2 T Lymphocytes
Francesco Dieli,Marita Troye-Blomberg,Juraj Ivanyi,Jean-Jacques Fournié,Alan M. Krensky,Marc Bonneville,Marie Alix Peyrat,Nadia Caccamo,Guido Sireci,Alfredo Salerno,Alfredo Salerno +10 more
TL;DR: Granulysin and perforin play a major role, which indicates that Vgamma9/Vdelta2 T lymphocytes directly contribute to a protective host response against M. tuberculosis infection.
Journal ArticleDOI
Iron Deficiency and Malaria among Children Living on the Coast of Kenya
Alice M Nyakeriga,Alice M Nyakeriga,Alice M Nyakeriga,Marita Troye-Blomberg,Jeffrey R. Dorfman,Neal Alexander,Rune Bäck,Moses Kortok,Alex K. Chemtai,Kevin Marsh,Thomas N. Williams +10 more
TL;DR: It is concluded that iron deficiency was associated with protection from mild clinical malaria in a cohort of children in coastal Kenya and possible mechanisms for this protection are discussed.