M
Manolis Kellis
Researcher at Massachusetts Institute of Technology
Publications - 448
Citations - 132627
Manolis Kellis is an academic researcher from Massachusetts Institute of Technology. The author has contributed to research in topics: Gene & Genome. The author has an hindex of 128, co-authored 405 publications receiving 112181 citations. Previous affiliations of Manolis Kellis include Broad Institute & Epigenomics AG.
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Exercise Training Remodels Inguinal White Adipose Tissue Through Adaptations in Innervation, Vascularization and the Extracellular Matrix
Pasquale Nigro,Maria Vamvini,Jie-Ying Yang,Tiziana Caputo,L L Ho,Danae Papadopoulos,Nicholas P. Carbone,Royce H. Conlin,Jie He,Michael F. Hirshman,Joseph D. White,Jacques Robidoux,Robert C. Hickner,Søren Nielsen,Bente Klarlund Pedersen,Manolis Kellis,Roeland J.W. Middelbeek,Laurie J. Goodyear +17 more
TL;DR: Using biochemical, imaging, and multi-omics analyses, it is found that 11-days of wheel running in male mice causes profound iWAT remodeling including decreased ECM deposition and increased vascularization and innervation.
Journal ArticleDOI
The changing face of genomics
TL;DR: A report on the 5th annual Advances in Genome Biology and Technology (AGBT) and Automation in DNA Mapping and Sequencing (AMS) meeting, Marco Island, USA, 4-7 February 2004.
Journal ArticleDOI
Publisher Correction: Evolution of enhanced innate immune evasion by SARS-CoV-2
Lucy Thorne,Mehdi Bouhaddou,Ann-Kathrin Barbara Reuschl,Lorena Zuliani-Alvarez,Benjamin J. Polacco,Adrian Pelin,Jyoti Batra,Matthew V. X. Whelan,Myra Hosmillo,Andrea Fossati,Roberta Ragazzini,Irwin Jungreis,Manisha Ummadi,Ajda Rojc,Jane Turner,Marie L. Bischof,Kirsten Obernier,Hannes Braberg,Margaret Soucheray,Alicia L. Richards,Kuei-Ho Chen,Bhavya Harjai,Danish Memon,Joseph Hiatt,Romel Rosales,Brian McGovern,Aminu S Jahun,Jacqueline M. Fabius,Kris M. White,Ian Goodfellow,Yasuyuki Takeuchi,Paola Bonfanti,Kevan M. Shokat,Natalia Jura,Kliment A. Verba,Mahdad Noursadeghi,Pedro Beltrao,Manolis Kellis,Danielle L. Swaney,Adolfo Garcia-Sastre,Clare Jolly,Greg J. Towers,Nevan J. Krogan +42 more
Posted ContentDOI
Cellular intelligence: dynamic specialization through non-equilibrium multi-scale compartmentalization
TL;DR: In this paper, the concepts of non-equilibrium tuning and compartmentalization are sufficient to model manifestations of cellular intelligence such as specialization, division, fusion and communication using the language of operads.
Posted ContentDOI
QClus: Robust and reliable preprocessing method for human heart snRNA-seq
Eloi Schmauch,Johannes Ojanen,Kyriaki Galani,Juho Jalkanen,Maija Hollmén,Jarmo Gunn,Tuomas Kiviniemi,Minna Kaikkonen-Määttä,Manolis Kellis,Suvi Linna-Kuosmanen +9 more
TL;DR: This study shows that, instead of using universal preprocessing methods, challenging tissue types, such as heart tissue, may benefit from methods that are more specific to the tissue under study, as QClus outperforms the other methods primarily due to improved integration of sample type-specific features.