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Mark M. Davis

Researcher at Stanford University

Publications -  623
Citations -  84251

Mark M. Davis is an academic researcher from Stanford University. The author has contributed to research in topics: T cell & T-cell receptor. The author has an hindex of 144, co-authored 581 publications receiving 74358 citations. Previous affiliations of Mark M. Davis include Washington University in St. Louis & University of Chicago.

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Computational resources for high-dimensional immune analysis from the Human Immunology Project Consortium.

TL;DR: Computational resources for high-dimensional immune analysis from the Human Immunology Project Consortium are provided.
Journal ArticleDOI

Topology and affinity of T-cell receptor mediated recognition of peptide-MHC complexes

TL;DR: Early data suggest that the affinity of the T-cell receptor for the peptide-MHC complex is extremely low, with a KD of approximately 10(-4)-10(-5)M, much weaker than most antibody-antigen interactions.
Journal ArticleDOI

Quantifying signaling-induced reorientation of T cell receptors during immunological synapse formation.

TL;DR: A 3D fluorescence quantitation method is used to show that T cell receptors are recruited in bulk within the first minute after the onset of activation and with velocities significantly greater than unrestricted diffusion.