M
Mark M. Davis
Researcher at Stanford University
Publications - 623
Citations - 84251
Mark M. Davis is an academic researcher from Stanford University. The author has contributed to research in topics: T cell & T-cell receptor. The author has an hindex of 144, co-authored 581 publications receiving 74358 citations. Previous affiliations of Mark M. Davis include Washington University in St. Louis & University of Chicago.
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Journal ArticleDOI
Induction of Rapid T Cell Activation and Tolerance by Systemic Presentation of an Orally Administered Antigen
TL;DR: Feeding multiple low doses of cytochrome c down-regulates the systemic immune response, which can be correlated with a reduction of antigen-specific T cells and not with immune deviation, suggest that systemic distribution of antigen contributes significantly to oral tolerance induction.
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Human Responses to Influenza Vaccination Show Seroconversion Signatures and Convergent Antibody Rearrangements
Katherine J. L. Jackson,Katherine J. L. Jackson,Yi Liu,Krishna M. Roskin,Jacob Glanville,Ramona A. Hoh,Katie Seo,Eleanor L. Marshall,Thaddeus C. Gurley,M. Anthony Moody,Barton F. Haynes,Emmanuel B. Walter,Hua-Xin Liao,Randy A. Albrecht,Adolfo García-Sastre,Javier Chaparro-Riggers,Arvind Rajpal,Jaume Pons,Birgitte B. Simen,Bozena Hanczaruk,Cornelia L. Dekker,Jonathan Laserson,Daphne Koller,Mark M. Davis,Mark M. Davis,Andrew Fire,Scott D. Boyd +26 more
TL;DR: The results indicate that microbes can induce specific signatures of immunoglobulin gene rearrangements and that pathogen exposure can potentially be assessed from B cell repertoires.
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Structure, expression and divergence of T-cell receptor β -chain variable regions
Phillip A. Patten,Takashi Yokota,Jonathan B. Rothbard,Yueh-hsiu Chien,Arai Ken-Ichi,Mark M. Davis +5 more
TL;DR: Analysis of three new T-cell receptor β-chain variable regions together with those in the literature indicates that they have both remarkable similarities and differences with those of immunoglobulin, indicating that important interactions may be occurring in these regions with polymorphic MHC determinants.
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Chronic myelogenous leukemia shapes host immunity by selective deletion of high-avidity leukemia-specific T cells
Jeffrey J. Molldrem,Peter P. Lee,Shreya Kant,Eric D. Wieder,Weidong Jiang,Sijie Lu,Changqing Wang,Mark M. Davis +7 more
TL;DR: Evidence that CML shapes the host immune response is provided and that leukemia outgrowth may result in part from leukemia-induced selective deletion of high-avidity PR1-specific T cells is provided.
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High-Dimensional Phenotypic Mapping of Human Dendritic Cells Reveals Interindividual Variation and Tissue Specialization.
Marcela Alcántara-Hernández,Rebecca Leylek,Lisa E. Wagar,Edgar G. Engleman,Tibor Keler,M. Peter Marinkovich,M. Peter Marinkovich,Mark M. Davis,Garry P. Nolan,Juliana Idoyaga +9 more
TL;DR: A multiparametric phenotypic characterization and unbiased analysis of human dendritic cells subsets in blood, tonsil, spleen, and skin reveals interindividual heterogeneity among DC subsets, especially cDC2s and profiles the heterogeneity of human DC subset among individuals and tissues, providing comprehensive insights for the development of DC‐based therapeutics.