M
Mark M. Davis
Researcher at Stanford University
Publications - 623
Citations - 84251
Mark M. Davis is an academic researcher from Stanford University. The author has contributed to research in topics: T cell & T-cell receptor. The author has an hindex of 144, co-authored 581 publications receiving 74358 citations. Previous affiliations of Mark M. Davis include Washington University in St. Louis & University of Chicago.
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Journal ArticleDOI
Rebooting Human Immunology
TL;DR: It is suggested that there are likely to be novel immunological mechanisms in long-lived, less fecund mammals such as human beings since they must remain healthy far longer than short-lived rodents in order for the species to survive.
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Pharmacodynamic and pharmacogenomic study of the nanoparticle conjugate of camptothecin CRLX101 for the treatment of cancer
Shikha Gaur,Yafan Wang,Leo Kretzner,Linling Chen,Terence Yen,Xiwei Wu,Yate Ching Yuan,Mark M. Davis,Yun Yen,Yun Yen +9 more
TL;DR: The expressions of key proteins that are inversely proportional with survival duration of the patients decreased after treatment with CRLX101, a camptothecin slow-release nanoparticle conjugate, which promising anti-tumor activity in heavily pre-treated and treatment resistant solid tumors.
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Multicenter Systems Analysis of Human Blood Reveals Immature Neutrophils in Males and During Pregnancy.
Jana Blazkova,Sarthak Gupta,Yudong Liu,Brice Gaudilliere,Edward A. Ganio,Christopher R. Bolen,Ron Saar-Dover,Gabriela K. Fragiadakis,Martin S. Angst,Sarfaraz Hasni,Nima Aghaeepour,David K. Stevenson,Nicole Baldwin,Esperanza Anguiano,Damien Chaussabel,Matthew C. Altman,Mariana J. Kaplan,Mark M. Davis,David Furman +18 more
TL;DR: The findings show novel sex differences in innate immunity and identify a common neutrophil signature in males and in pregnant women, which is found at higher levels in young but not older males compared with females.
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Global analysis of shared T cell specificities in human non-small cell lung cancer enables HLA inference and antigen discovery.
Shin Heng Chiou,Diane Tseng,Alexandre Reuben,Vamsee Mallajosyula,Irene S. Molina,Stephanie D. Conley,Julie Wilhelmy,Alana McSween,Xinbo Yang,Daisuke Nishimiya,Rahul Sinha,Barzin Y. Nabet,Chunlin Wang,Joseph B. Shrager,Mark F. Berry,Leah M. Backhus,Natalie S. Lui,Heather A. Wakelee,Joel W. Neal,Sukhmani K. Padda,Gerald J. Berry,Alberto Delaidelli,Poul H. Sorensen,Elena Sotillo,Patrick Tran,Jalen Benson,Rebecca Richards,Louai Labanieh,Dorota Klysz,David M. Louis,Steven A. Feldman,Maximilian Diehn,Irving L. Weissman,Jianjun Zhang,Ignacio I. Wistuba,P. Andrew Futreal,John V. Heymach,K. Christopher Garcia,Crystal L. Mackall,Mark M. Davis +39 more
TL;DR: The findings suggest that this cross-reactivity may underlie the presence of virus-specific T cells in tumor infiltrates and that pathogen cross- reactivity may be a feature of multiple cancers.
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Integrated analysis of plasma and single immune cells uncovers metabolic changes in individuals with COVID-19.
Jihoon W Lee,Yapeng Su,Yapeng Su,Priyanka Baloni,Daniel Chen,Ana Jimena Pavlovitch-Bedzyk,Dan Yuan,Venkata R Duvvuri,Rachel Ng,Jongchan Choi,Jingyi Xie,Rongyu Zhang,Kim Murray,Sergey A. Kornilov,Brett Smith,Andrew T. Magis,Dave S.B. Hoon,Jennifer Hadlock,Jason D Goldman,Nathan D. Price,Nathan D. Price,Raphael Gottardo,Raphael Gottardo,Mark M. Davis,Leroy Hood,Philip D. Greenberg,Philip D. Greenberg,James R. Heath,James R. Heath +28 more
TL;DR: In this article, metabolic changes associated with the peripheral immune response of 198 individuals with COVID-19 through an integrated analysis of plasma metabolite and protein levels as well as single-cell multiomics analyses from serial blood draws collected during the first week after clinical diagnosis.