M
Michael Snyder
Researcher at Stanford University
Publications - 938
Citations - 150929
Michael Snyder is an academic researcher from Stanford University. The author has contributed to research in topics: Gene & Genome. The author has an hindex of 169, co-authored 840 publications receiving 130225 citations. Previous affiliations of Michael Snyder include Wyss Institute for Biologically Inspired Engineering & Public Health Research Institute.
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Transglutaminase 4 as a prostate autoantigen in male subfertility
Nils Landegren,Nils Landegren,Donald Sharon,Donald Sharon,Anthony K. Shum,Imran S. Khan,Kayla J. Fasano,Åsa Hallgren,Åsa Hallgren,Caroline Kampf,Eva Freyhult,Brita Ardesjö-Lundgren,Mohammad Alimohammadi,Mohammad Alimohammadi,Mohammad Alimohammadi,Sandra Rathsman,Jonas F. Ludvigsson,Dan Lundh,Ruben Dario Motrich,Virginia Elena Rivero,Lawrence Fong,Aleksander Giwercman,Jan Gustafsson,Jaakko Perheentupa,Eystein S. Husebye,Mark S. Anderson,Michael Snyder,Olle Kämpe,Olle Kämpe +28 more
TL;DR: It is reported that the prostatic secretory molecule tranglutaminase 4 (TGM4) is a male-specific autoantigen in APS1 patients that could contribute to subfertility and confirmed in AIRE-deficient mice that TGM4 autoantibodies lead to a destructive prostatitis.
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The Kar3p Kinesin-related Protein Forms a Novel Heterodimeric Structure with Its Associated Protein Cik1p
TL;DR: Mapping of the interaction domains of the two proteins by two-hybrid analyses indicates that Kar3p and Cik1p associate in a highly specific manner along the lengths of their respective coiled-coil domains, demonstrating that the Kar3-Cik1 complex has a novel heterodimeric structure not observed previously for kinesin complexes.
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iPOP Goes the World: Integrated Personalized Omics Profiling and the Road toward Improved Health Care
TL;DR: Integrative personal omics profiling (iPOP) is a stepping stone to a new road to personalized health care and may improve disease risk assessment, accuracy of diagnosis, disease monitoring, targeted treatments, and understanding the biological processes of disease states for their prevention.
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Design optimization methods for genomic DNA tiling arrays
Paul Bertone,Valery Trifonov,Joel Rozowsky,Falk Schubert,Olof Emanuelsson,John E. Karro,Ming-Yang Kao,Michael Snyder,Mark Gerstein +8 more
TL;DR: A recent development in microarray research entails the unbiased coverage, or tiling, of genomic DNA for the large-scale identification of transcribed sequences and regulatory elements, and two algorithms for finding an optimal tile path composed of longer sequence tiles are developed.
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Long-Read Sequencing - A Powerful Tool in Viral Transcriptome Research.
TL;DR: Two important LRS technologies have been developed during the past few years, including single-molecule, real-time sequencing by Pacific Biosciences, and nanopore sequencing by Oxford Nanopore Technologies.