M
Michael Snyder
Researcher at Stanford University
Publications - 938
Citations - 150929
Michael Snyder is an academic researcher from Stanford University. The author has contributed to research in topics: Gene & Genome. The author has an hindex of 169, co-authored 840 publications receiving 130225 citations. Previous affiliations of Michael Snyder include Wyss Institute for Biologically Inspired Engineering & Public Health Research Institute.
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Proceedings Article
YMD: a microarray database for large-scale gene expression analysis.
Kei-Hoi Cheung,Kevin P. White,Janet Hager,Mark Gerstein,Valerie Reinke,Kenneth Nelson,Peter Masiar,Ranjana Srivastava,Yuli Li,Ju Li,Hongyu Zhao,Jinming Li,David B. Allison,Michael Snyder,Perry L. Miller,Kenneth R. Williams +15 more
TL;DR: The Yale Microarray Database (YMD) is a robust database system that allows efficient data storage, retrieval, secure access, data dissemination, and integrated data analyses for microarray researchers at Yale and their collaborators.
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Haplotype structure and positive selection at TLR1
Christopher Heffelfinger,Andrew J. Pakstis,William C. Speed,Allison P Clark,Eva Haigh,Rixun Fang,Mahohar R Furtado,Kenneth K. Kidd,Michael Snyder +8 more
TL;DR: Interestingly, 602Ser, which shows signatures of selection, inhibits TLR1 surface trafficking and subsequent activation of NFκB upon recognition of a ligand, suggesting that reducedTLR1 activity may be beneficial for human health.
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High Throughput Sequencing and Assessing Disease Risk
Shannon Rego,Michael Snyder +1 more
TL;DR: High-throughput sequencing has dramatically improved the ability to determine and diagnose the underlying causes of human disease and will likely continue to influence this area of disease research as more and more individuals undergo sequencing and the authors better understand the significance of variation across the genome.
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Disruption of mesoderm formation during cardiac differentiation due to developmental exposure to 13-cis-retinoic acid
Qing Liu,Kevin Van Bortle,Yue Zhang,Ming-Tao Zhao,Joe Z. Zhang,Benjamin Geller,Joshua J. Gruber,Chao Jiang,Joseph C. Wu,Michael Snyder +9 more
TL;DR: The molecular mechanisms underlying INN-induced perturbation during mesodermal differentiation in the context of cardiac development are identified and the utility of human stem cells is highlighted as an alternative system for investigating congenital diseases of newborns that arise as a result of maternal drug exposure during pregnancy.
Journal ArticleDOI
Toward More Transparent and Reproducible Omics Studies Through a Common Metadata Checklist and Data Publications.
Eugene Kolker,Eugene Kolker,Vural Ozdemir,Lennart Martens,Lennart Martens,William S. Hancock,Gordon A. Anderson,Nathaniel Anderson,Sukru Aynacioglu,Ancha Baranova,Shawn R. Campagna,Rui Chen,John Choiniere,Stephen P. Dearth,Wu-chun Feng,Lynnette R. Ferguson,Geoffrey C. Fox,Dmitrij Frishman,Robert L. Grossman,Allison Heath,Roger Higdon,Roger Higdon,Mara H. Hutz,Imre Janko,Lihua Jiang,Sanjay Joshi,Alexander Kel,Joseph W. Kemnitz,Isaac S. Kohane,Natali Kolker,Natali Kolker,Doron Lancet,Elaine Lee,Weizhong Li,Andrey Lisitsa,Adrián LLerena,Courtney MacNealy-Koch,Jean-Claude Marshall,Paola Masuzzo,Paola Masuzzo,Amanda L. May,George I. Mias,Matthew E. Monroe,Elizabeth Montague,Elizabeth Montague,Sean D. Mooney,Alexey I. Nesvizhskii,Santosh Noronha,Gilbert S. Omenn,Harsha Rajasimha,Preveen Ramamoorthy,Jerry Sheehan,Larry Smarr,Charles V. Smith,Todd M. Smith,Michael Snyder,Srikanth Rapole,Sanjeeva Srivastava,Larissa Stanberry,Larissa Stanberry,Elizabeth Stewart,Stefano Toppo,Peter Uetz,Kenneth Verheggen,Kenneth Verheggen,Brynn H. Voy,Louise Warnich,Steven W. Wilhelm,Gregory Yandl +68 more
TL;DR: The proposed omics metadata checklist will serve as a common denominator to guide experimental design, capture important parameters, and be used as a standard format for stand-alone data publications and allow for appropriate attribution to data generators and infrastructure science builders in the post-genomics era.