M
Michael Snyder
Researcher at Stanford University
Publications - 938
Citations - 150929
Michael Snyder is an academic researcher from Stanford University. The author has contributed to research in topics: Gene & Genome. The author has an hindex of 169, co-authored 840 publications receiving 130225 citations. Previous affiliations of Michael Snyder include Wyss Institute for Biologically Inspired Engineering & Public Health Research Institute.
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Sushi.R: flexible, quantitative and integrative genomic visualizations for publication-quality multi-panel figures
TL;DR: This work presents Sushi.R, an R/Bioconductor package that allows flexible integration of genomic visualizations into highly customizable, publication-ready, multi-panel figures from common genomic data formats including Browser Extensible Data (BED), bedGraph and Browser extensible Data Paired-End (BedPE).
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Bent DNA at a yeast autonomously replicating sequence
TL;DR: The existence of bent DNA is shown at a yeast autonomously replicating sequence (ARS1), a putative replication origin, and may be involved in transcription termination or the prevention of nucleosome assembly in this region.
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Understanding transcriptional regulation by integrative analysis of transcription factor binding data
Chao Cheng,Roger P. Alexander,Rengqiang Min,Jing Leng,Kevin Y. Yip,Kevin Y. Yip,Joel Rozowsky,Koon-Kiu Yan,Xianjun Dong,Sarah Djebali,Yijun Ruan,Carrie A. Davis,Piero Carninci,Timo Lassman,Thomas R. Gingeras,Roderic Guigó,Ewan Birney,Zhiping Weng,Michael Snyder,Mark Gerstein +19 more
TL;DR: A notable difference is revealed in the prediction accuracy of expression levels of transcription start sites (TSSs) captured by different technologies and RNA extraction protocols, which implies that these features regulate transcription in a highly coordinated manner.
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A multipurpose transposon system for analyzing protein production, localization, and function in Saccharomyces cerevisiae
TL;DR: A multifunctional, transposon-based system that simultaneously generates constructs for all the above analyses and is suitable for mutagenesis of any given Saccharomyces cerevisiae gene is developed.
Journal ArticleDOI
CREB Binds to Multiple Loci on Human Chromosome 22
Ghia Euskirchen,Thomas Royce,Paul Bertone,Rebecca Martone,John L. Rinn,F. Kenneth Nelson,Fred Sayward,Nicholas M. Luscombe,Perry L. Miller,Mark Gerstein,Sherman M. Weissman,Michael Snyder +11 more
TL;DR: Mapping for the first time the binding distribution of CREB along an entire human chromosome revealed 215 binding sites corresponding to 192 different loci and 100 annotated potential gene targets, providing novel molecular insights into how CREB mediates its functions in humans.