Michael Snyder

TL;DR: This review discusses the construction of different types of protein arrays, and their numerous and diverse applications for drug discovery and development.

TL;DR: A series of methods for identification of genetic variants and genotypes with clinical associations, phasing genetic data and using Mendelian inheritance for quality control are presented, providing predictive genetic information about risk for rare disease phenotypes and response to pharmacological therapy in single individuals and father-mother-child trios.

TL;DR: The Interpretome is presented, a system for private genome interpretation, which contains all genotype information in client-side interpretation scripts, supported by server-side databases, and provides state-of-the-art analyses for teaching clinical implications of personal genomics, including disease risk assessment and pharmacogenomics.

TL;DR: The HDO array platform provides a far more robust array system by all measures than PCR-based arrays, all of which is directly attributable to the large number of probes available.

TL;DR: It is indicated that de novo and rare mutations in HSPA1L are associated with IBD and provide insights into the pathogenesis of IBD, and also expand the understanding of the roles of HSP70s in human disease.