M
Michael Snyder
Researcher at Stanford University
Publications - 938
Citations - 150929
Michael Snyder is an academic researcher from Stanford University. The author has contributed to research in topics: Gene & Genome. The author has an hindex of 169, co-authored 840 publications receiving 130225 citations. Previous affiliations of Michael Snyder include Wyss Institute for Biologically Inspired Engineering & Public Health Research Institute.
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Journal ArticleDOI
Classification of human genomic regions based on experimentally determined binding sites of more than 100 transcription-related factors.
Kevin Y. Yip,Chao Cheng,Nitin Bhardwaj,James B. Brown,Jing Leng,Anshul Kundaje,Joel Rozowsky,Ewan Birney,Peter J. Bickel,Michael Snyder,Mark Gerstein +10 more
TL;DR: Three pairs of regions exhibit intricate differences in chromosomal locations, chromatin features, factors that bind them, and cell-type specificity, and the machine learning approach enables us to identify features potentially general to all transcription factors, including those not included in the data.
Journal ArticleDOI
Sexual dimorphism in mammalian gene expression.
John L. Rinn,Michael Snyder +1 more
TL;DR: Findings from microarrays and other methods are providing new insights into the molecular and genetic differences that dictate the different behaviors and physiologies of mammalian sexes.
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Mass spectrometry-based metabolomics: a guide for annotation, quantification and best reporting practices
Saleh Alseekh,Asaph Aharoni,Yariv Brotman,Kévin Contrepois,John C. D’Auria,Jan Ewald,Jennifer C. Ewald,Paul D. Fraser,Patrick Giavalisco,Robert Hall,Matthias Heinemann,Hannes Link,Jie Luo,Steffen Neumann,Jens Nielsen,Leonardo Perez de Souza,Kazuki Saito,Uwe Sauer,Frank C. Schroeder,Stefan Schuster,Gary Siuzdak,Aleksandra Skirycz,Lloyd W. Sumner,Michael Snyder,Huiru Tang,Takayuki Tohge,Yulan Wang,Weiwei Wen,Si Wu,Guowang Xu,Nicola Zamboni,Alisdair R. Fernie +31 more
TL;DR: In this article, the authors present guidelines covering sample preparation, replication and randomization, quantification, recovery and recombination, ion suppression and peak misidentification, as a means to enable high-quality reporting of liquid chromatography and gas chromatography-mass spectrometry-derived data.
Journal ArticleDOI
SBF Cell Cycle Regulator as a Target of the Yeast PKC-MAP Kinase Pathway
TL;DR: Genetic studies, coimmunoprecipitation experiments, and analysis of protein phosphorylation indicate that the SBF transcription factor, an important regulator of gene expression at the G1 to S phase cell cycle transition, is a target of the Slt2p(Mpk1p) MAP kinase.
Journal ArticleDOI
Principles of regulatory information conservation between mouse and human
Yong Cheng,Zhihai Ma,Bong Hyun Kim,Weisheng Wu,Weisheng Wu,Philip Cayting,Alan P. Boyle,Vasavi Sundaram,Xiaoyun Xing,Nergiz Dogan,Jingjing Li,Ghia Euskirchen,Shin Lin,Yiing Lin,Yiing Lin,Axel Visel,Axel Visel,Axel Visel,Trupti Kawli,Xinqiong Yang,Dorrelyn Patacsil,Cheryl A. Keller,Belinda Giardine,Anshul Kundaje,Ting Wang,Len A. Pennacchio,Len A. Pennacchio,Zhiping Weng,Ross C. Hardison,Michael Snyder +29 more
TL;DR: Using the genome-wide transcription factor occupancy repertoires, associated epigenetic signals, and co-association patterns, several evolutionary principles of gene regulatory features operating since the mouse and human lineages diverged are deduced.