M
Michael Snyder
Researcher at Stanford University
Publications - 938
Citations - 150929
Michael Snyder is an academic researcher from Stanford University. The author has contributed to research in topics: Gene & Genome. The author has an hindex of 169, co-authored 840 publications receiving 130225 citations. Previous affiliations of Michael Snyder include Wyss Institute for Biologically Inspired Engineering & Public Health Research Institute.
Papers
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Journal ArticleDOI
Abstract 9501: Single-Cell Transcriptomic Analysis and Patient-Specific iPSCs Reveal Dysfunctional Coronary Arterial Endothelial Cells in Hypoplastic Left Heart Syndrome
Zhiyun Yu,Xiang Zhao,Ziyi Liu,Yu Lu,Minzhe Guo,Lei Tian,Timothy J. Nelson,Nian Wang,Seema Mital,David Chitayat,Joseph C. Wu,Marlene Rabinovitch,Sean Wu,Michael Snyder,Yifei Miao,Mingxia Gu +15 more
TL;DR: In this paper , the authors used single cell RNA-seq and subsequent gene ontology analysis to study the arterial EC phenotypes, and generated iPSC-arterial ECs (AECs, CDH5676 +====== CXCR4====== +====== NT5E====== -/low====== AEC progenitors.
Journal ArticleDOI
The prognostic impact of immune-related adverse events in real-world patients with metastatic melanoma treated with single-agent and combination immune checkpoint blockade.
Alexander Watson,Siddhartha Goutam,Igor Stukalin,Benjamin W. Ewanchuk,Michael Snyder,Daniel E. Meyers,Aliyah Pabani,Winson Y. Cheung,Daniel Y.C. Heng,Tina Cheng,Jose Monzon,Vishal Navani +11 more
TL;DR: The association of irAEs and improved survival outcomes in MM, including those patients treated with combination ICB, are supported, and hospitalization for irAE, and ICB re-challenge post-irAE, were further associated with improved outcomes.
Patent
Method for High Throughput Screening for Anitbodies and Proteins Inducing Apoptosis
TL;DR: High throughput assays used to identify antibodies and proteins that induce cell death are described in this paper, but it is not necessary to identify the antigens the antibodies are reactive with prior to performing the assays.
Posted ContentDOI
Low expression of EXOSC2 protects against clinical COVID-19 and impedes SARS-CoV-2 replication
Tobias Moll,Valerie Odon,Calum Harvey,Mark O. Collins,Andrew A. Peden,John P Franklin,Emily J Graves,J. N. Marshall,Cleide dos Santos Souza,Sai Zhang,Lydia M. Castelli,Guillaume M. Hautbergue,Mimoun Azzouz,David E. Gordon,Nevan J. Krogan,Laura Ferraiuolo,Michael Snyder,Pamela J. Shaw,Jan Rehwinkel,Johnathan Cooper-Knock +19 more
TL;DR: Genetic evidence and in vitro experiments with live virus suggest EXOSC2 depletion can reduce SARS-CoV-2 replication without significant toxicity.
Journal ArticleDOI
Distinct factors associated with short-term and long-term weight loss induced by low-fat or low-carbohydrate diet intervention
Xiao Li,Dalia Perelman,Ariel K Leong,Gabriela K. Fragiadakis,Christopher D. Gardner,Michael Snyder +5 more
TL;DR: In this article , a secondary analysis of dietary, metabolic, and molecular data collected from 609 participants before, during, and after a 1-year weight-loss intervention with either a healthy low-carbohydrate (HLC) or healthy lowfat (HLF) diet was conducted to understand what determines the success of short and long-term weight loss.