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Michel Aigle

Researcher at University of Lyon

Publications -  88
Citations -  6922

Michel Aigle is an academic researcher from University of Lyon. The author has contributed to research in topics: Saccharomyces cerevisiae & Gene. The author has an hindex of 42, co-authored 88 publications receiving 6758 citations. Previous affiliations of Michel Aigle include University of Bordeaux & École normale supérieure de Lyon.

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Genome evolution in yeasts

TL;DR: Analysis of chromosome maps and genome redundancies reveal that the different yeast lineages have evolved through a marked interplay between several distinct molecular mechanisms, including tandem gene repeat formation, segmental duplication, a massive genome duplication and extensive gene loss.
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The complete DNA sequence of yeast chromosome III.

Stephen G. Oliver, +146 more
- 07 May 1992 - 
TL;DR: The entire DNA sequence of chromosome III of the yeast Saccharomyces cerevisiae has been determined, which is the first complete sequence analysis of an entire chromosome from any organism.
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Identification of yeast strains using the polymerase chain reaction

TL;DR: A novel strategy has been developed for identifying yeast strain employing polymerase chain reaction technology using customised oligonucleotides, some regions of the yeast genome between δ elements are amplified to give an 'amplified' sequence polymorphisml characteristic of the strains.
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Alteration of a yeast SH3 protein leads to conditional viability with defects in cytoskeletal and budding patterns.

TL;DR: The gene RVS167, which shows reduced viability and abnormal cell morphology upon carbon and nitrogen starvation, could be implicated in cytoskeletal reorganization in response to environmental stresses and could act in the budding site selection mechanism.