P
Peter S. Nelson
Researcher at Fred Hutchinson Cancer Research Center
Publications - 497
Citations - 57568
Peter S. Nelson is an academic researcher from Fred Hutchinson Cancer Research Center. The author has contributed to research in topics: Prostate cancer & Cancer. The author has an hindex of 96, co-authored 425 publications receiving 47923 citations. Previous affiliations of Peter S. Nelson include University of Washington & National Institutes of Health.
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Journal ArticleDOI
A proteolytic modification of AIM promotes its renal excretion.
Tomoko Yamazaki,Ryoichi Sugisawa,Emiri Hiramoto,Ryosuke Takai,Ayaka Matsumoto,Yoshie Senda,Katsuhiko Nakashima,Peter S. Nelson,Jared M. Lucas,Andrew Morgan,Zhenghua Li,Ken Ichi Yamamura,Satoko Arai,Toru Miyazaki,Toru Miyazaki +14 more
TL;DR: Interestingly, cleaved AIM retained a comparable potency with full-length AIM in facilitating the clearance of dead cell debris in injured kidney, which is a key response in the recovery of acute kidney injury.
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Third international conference on innovations and challenges in prostate cancer: prevention, detection and treatment.
Peter R. Carroll,June M. Chan,Anthony V. D'Amico,Edward P. Gelmann,Peter Iversen,Laurence Klotz,Joel B. Nelson,Peter S. Nelson,William G. Nelson,William Oh,Neal Rosen,Mark A. Rubin,Howard M. Sandler,William R. Sellers,Matthew R. Smith,Jianfeng Xu,Mary C. Mcmann,Philip W. Kantoff +17 more
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Establishing a cryopreservation protocol for patient-derived xenografts of prostate cancer.
Laura H Porter,Mitchell G. Lawrence,Mitchell G. Lawrence,Hong Wang,Ashlee K. Clark,Andrew Bakshi,Andrew Bakshi,Daisuke Obinata,David L Goode,David L Goode,Melissa Papargiris,Melissa Papargiris,Mural,David Clouston,Andrew Ryan,Sam Norden,Eva Corey,Peter S. Nelson,Peter S. Nelson,John T. Isaacs,Jeremy Grummet,John Kourambas,Shahneen Sandhu,Shahneen Sandhu,Declan G. Murphy,Declan G. Murphy,David Pook,Mark Frydenberg,Renea A. Taylor,Gail P. Risbridger,Gail P. Risbridger +30 more
TL;DR: This study compared three differentCryopreservation protocols to identify a method that can be used to reproducibly cryopreserve a diverse cohort of prostate cancer PDX models.
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Unchecked oxidative stress in skeletal muscle prevents outgrowth of disseminated tumour cells
Sarah B. Crist,Travis Nemkov,Ruth Dumpit,Jinxiang Dai,Stephen J. Tapscott,Lawrence D. True,Alexander Swarbrick,Lucas B. Sullivan,Peter S. Nelson,Kirk C. Hansen,Cyrus M. Ghajar +10 more
TL;DR: It is shown that DTCs traffic to and persist within skeletal muscle in mice and in humans, which raises the question of how this tissue suppresses colonization, and reveals a profound metabolic bottleneck imposed on D TCs and sustained by skeletal muscle.
Journal ArticleDOI
Selective androgen receptor modulators activate the canonical prostate cancer androgen receptor program and repress cancer growth.
Michael D. Nyquist,Lisa S Ang,Alexandra Corella,Ilsa Coleman,Michael P. Meers,Anthony J Christiani,Cordell Pierce,Derek H. Janssens,Hannah E Meade,Arnab Bose,Lauren Brady,Timothy D. Howard,Navonil De Sarkar,Sander B. Frank,Ruth Dumpit,James T Dalton,Eva Corey,Stephen R. Plymate,Michael C. Haffner,Elahe A. Mostaghel,Elahe A. Mostaghel,Peter S. Nelson +21 more
TL;DR: In this paper, selective AR modulators (SARMs) were used to treat prostate cancer in both castration sensitive and castration resistant prostate cancer patients in vitro and in vivo.