P
Peter S. Nelson
Researcher at Fred Hutchinson Cancer Research Center
Publications - 497
Citations - 57568
Peter S. Nelson is an academic researcher from Fred Hutchinson Cancer Research Center. The author has contributed to research in topics: Prostate cancer & Cancer. The author has an hindex of 96, co-authored 425 publications receiving 47923 citations. Previous affiliations of Peter S. Nelson include University of Washington & National Institutes of Health.
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Journal ArticleDOI
Deconstructing tumor heterogeneity: the stromal perspective.
Renee E. Vickman,Douglas V. Faget,Philip A. Beachy,David J. Beebe,Neil A. Bhowmick,Edna Cukierman,Wu-Min Deng,James G. Granneman,Jeffrey Hildesheim,Raghu Kalluri,Ken S. Lau,Ernst Lengyel,Joakim Lundeberg,Jorge Moscat,Peter S. Nelson,Kristian Pietras,Katerina Politi,Ellen Puré,Ruth Scherz-Shouval,Mara H. Sherman,David A. Tuveson,Ashani T. Weeraratna,Richard M. White,Melissa H. Wong,Elisa C. Woodhouse,Ying Zheng,Simon W. Hayward,Sheila A. Stewart +27 more
TL;DR: The opposing roles of tumor supportive versus suppressive stroma and how cellular composition and function may be altered during disease progression were explored as an effort to identify current challenges and knowledge gaps in the field.
Journal ArticleDOI
Identification and characterization of novel SNPs in CHEK2 in Ashkenazi Jewish men with prostate cancer
Marc Tischkowitz,Marc Tischkowitz,Ahmet Yilmaz,Ahmet Yilmaz,Long Q. Chen,Danielle M. Karyadi,Danielle M. Karyadi,David J. Novak,David J. Novak,Tomas Kirchhoff,Nancy Hamel,Sean V. Tavtigian,Suzanne Kolb,Tarek A. Bismar,Raquel Aloyz,Peter S. Nelson,Lee Hood,Steven A. Narod,Kirsten White,Elaine A. Ostrander,William B. Isaacs,Kenneth Offit,Kathleen A. Cooney,Janet L. Stanford,William D. Foulkes,William D. Foulkes +25 more
TL;DR: The results suggest that germline CHEK2 mutations have a minor role in, if any, PRCA susceptibility in AJ men.
Journal ArticleDOI
Performance of PCA3 and TMPRSS2:ERG urinary biomarkers in prediction of biopsy outcome in the Canary Prostate Active Surveillance Study (PASS).
Lisa F. Newcomb,Lisa F. Newcomb,Yingye Zheng,Anna Faino,Daniella Bianchi-Frias,Matthew R. Cooperberg,Marshall D. Brown,James D. Brooks,Atreya Dash,Michael D. Fabrizio,Martin E. Gleave,Michael A. Liss,Todd M. Morgan,Ian M. Thompson,Andrew A. Wagner,Peter R. Carroll,Peter S. Nelson,Daniel W. Lin,Daniel W. Lin +18 more
TL;DR: PCA3 but not T2:ERG was associated with cancer reclassification in the first surveillance biopsy but has negligible improvement over clinical variables alone in ROC or DCA analyses.
Journal ArticleDOI
Integrative analysis of N-linked human glycoproteomic data sets reveals PTPRF ectodomain as a novel plasma biomarker candidate for prostate cancer.
Theodore E. Whitmore,Amelia Peterson,Ted Holzman,Ashley Eastham,Lynn M. Amon,Martin W. McIntosh,Adrian Ozinsky,Peter S. Nelson,Daniel Martin +8 more
TL;DR: The identification of the extracellular domain of protein tyrosine phosphatase receptor type F (PTPRF) was of particular interest, and it is demonstrated that the PTPRF E-subunit is more abundant in human prostate tumor tissue compared to normal control and also detectable in murine plasma by immunoblot and ELISA.
Journal ArticleDOI
Inherited TP53 Variants and Risk of Prostate Cancer
Kara N. Maxwell,Kara N. Maxwell,Heather H. Cheng,Heather H. Cheng,Jacquelyn Powers,Roman Gulati,Elisa Ledet,Casey Morrison,Anh D. Le,Ryan Hausler,Ryan Hausler,Jill E. Stopfer,Sophie Hyman,Wendy Kohlmann,Anne Naumer,Jennie Vagher,Samantha Greenberg,Lorraine V. Naylor,Mercy Y. Laurino,Eric Q. Konnick,Brian H. Shirts,Saud H. AlDubayan,Saud H. AlDubayan,Eliezer M. Van Allen,Eliezer M. Van Allen,Bastien Nguyen,Joseph Vijai,Wassim Abida,Maria I. Carlo,Marianne E Dubard-Gault,Marianne E Dubard-Gault,Daniel J. Lee,Daniel J. Lee,Luke Maese,Luke Maese,Diana Mandelker,Bruce Montgomery,Bruce Montgomery,Michael J. Morris,Piper Nicolosi,Robert L. Nussbaum,Lauren E. Schwartz,Zsofia K. Stadler,Judy Garber,Kenneth Offit,Joshua D. Schiffman,Joshua D. Schiffman,Peter S. Nelson,Peter S. Nelson,Oliver Sartor,Michael Walsh,Colin C. Pritchard +51 more
TL;DR: In this paper, a multi-institutional retrospective study characterizes prostate cancer incidence in a cohort of Li-Fraumeni syndrome (LFS) males and gTP53 prevalence in a prostate cancer cohort.